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Photocatalytic glucose-appended bio-compatible Ir(iii) anticancer complexes
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Zhu, Zilin, Wei, Li, Lai, Yidan, Carter, Oliver W. L., Banerjee, Samya, Sadler, Peter J. and Huang, Huaiyi (2022) Photocatalytic glucose-appended bio-compatible Ir(iii) anticancer complexes. Dalton Transactions, 51 (29). pp. 10875-10879. doi:10.1039/d2dt01134d ISSN 1477-9234.
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WRAP-Photocatalytic-glucose-appended-bio-compatible-anticancer-complexes-22.pdf - Accepted Version Embargoed item. Restricted access to Repository staff only until 20 July 2023. Contact author directly, specifying your specific needs. - Requires a PDF viewer. Download (812Kb) |
Official URL: https://doi.org/10.1039/d2dt01134d
Abstract
A glucose-appended bio-compatible Ir(iii) complex which absorbs light strongly, photo-catalytically oxidizes cellular coenzymes NAD(P)H, and decreases the mitochondrial membrane potential, resulting in cancer cell apoptosis and necrosis.
| Item Type: | Journal Article | ||||||||||||||||||||||||||||||
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| Subjects: | Q Science > QD Chemistry Q Science > QP Physiology R Medicine > RS Pharmacy and materia medica |
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| Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||||||||||||||||||||||||||||
| SWORD Depositor: | Library Publications Router | ||||||||||||||||||||||||||||||
| Library of Congress Subject Headings (LCSH): | Antineoplastic agents -- Research, Drugs -- Design, Photocatalysis, Chemistry, Inorganic, Cancer -- Chemotherapy, Metals in the body, Metals -- Therapeutic use | ||||||||||||||||||||||||||||||
| Journal or Publication Title: | Dalton Transactions | ||||||||||||||||||||||||||||||
| Publisher: | Royal Society of Chemistry (RSC) | ||||||||||||||||||||||||||||||
| ISSN: | 1477-9234 | ||||||||||||||||||||||||||||||
| Official Date: | 7 August 2022 | ||||||||||||||||||||||||||||||
| Dates: |
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| Volume: | 51 | ||||||||||||||||||||||||||||||
| Number: | 29 | ||||||||||||||||||||||||||||||
| Page Range: | pp. 10875-10879 | ||||||||||||||||||||||||||||||
| DOI: | 10.1039/d2dt01134d | ||||||||||||||||||||||||||||||
| Status: | Peer Reviewed | ||||||||||||||||||||||||||||||
| Publication Status: | Published | ||||||||||||||||||||||||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||||||||||||||||||||||||
| Date of first compliant deposit: | 31 August 2022 | ||||||||||||||||||||||||||||||
| RIOXX Funder/Project Grant: |
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