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Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC) : a joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPGBI) and the British Society of Gastroenterology (BSG)
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(2022) Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC) : a joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPGBI) and the British Society of Gastroenterology (BSG). Gut, 71 (10). pp. 1939-1962. doi:10.1136/gutjnl-2022-327985 ISSN 0017-5749. [ 🗎 Public]. [ (✓) hoa:511 ]
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WRAP-Faecal-immunochemical-testing-FIT-patients-colorectal-cancer-guideline-22.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (9Mb) | Preview |
Official URL: https://doi.org/10.1136/gutjnl-2022-327985
Abstract
Faecal immunochemical testing (FIT) has a high sensitivity for the detection of colorectal cancer (CRC). In a symptomatic population FIT may identify those patients who require colorectal investigation with the highest priority. FIT offers considerable advantages over the use of symptoms alone, as an objective measure of risk with a vastly superior positive predictive value for CRC, while conversely identifying a truly low risk cohort of patients. The aim of this guideline was to provide a clear strategy for the use of FIT in the diagnostic pathway of people with signs or symptoms of a suspected diagnosis of CRC. The guideline was jointly developed by the Association of Coloproctology of Great Britain and Ireland/British Society of Gastroenterology, specifically by a 21-member multidisciplinary guideline development group (GDG). A systematic review of 13 535 publications was undertaken to develop 23 evidence and expert opinion-based recommendations for the triage of people with symptoms of a suspected CRC diagnosis in primary care. In order to achieve consensus among a broad group of key stakeholders, we completed an extended Delphi of the GDG, and also 61 other individuals across the UK and Ireland, including by members of the public, charities and primary and secondary care. Seventeen research recommendations were also prioritised to inform clinical management. [Abstract copyright: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.]
| Item Type: | Journal Article | ||||||||
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||
| SWORD Depositor: | Library Publications Router | ||||||||
| Journal or Publication Title: | Gut | ||||||||
| Publisher: | B M J Group | ||||||||
| ISSN: | 0017-5749 | ||||||||
| Official Date: | 7 September 2022 | ||||||||
| Dates: |
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| Volume: | 71 | ||||||||
| Number: | 10 | ||||||||
| Page Range: | pp. 1939-1962 | ||||||||
| DOI: | 10.1136/gutjnl-2022-327985 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||
| Date of first compliant deposit: | 5 August 2022 | ||||||||
| Date of first compliant Open Access: | 5 August 2022 |
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