The Library
The DAPA-DIET study : metabolic response to Dapagliflozin combined with dietary carbohydrate restriction in patients with Type 2 Diabetes mellitus and obesity—a longitudinal cohort study
Tools
Tools
Tools
Hanson, Petra, Randeva, Harpal S., Cuthbertson, D., O'Hare, Paul J., Parsons, Nicholas R., Chatha, Kamaljit , Reidy, G., Weickert, Martin O. and Barber, Thomas M. (2022) The DAPA-DIET study : metabolic response to Dapagliflozin combined with dietary carbohydrate restriction in patients with Type 2 Diabetes mellitus and obesity—a longitudinal cohort study. Endocrinology, Diabetes & Metabolism, 5 (6). e381. doi:10.1002/edm2.381 ISSN 2398-9238. [ 🗎 Public]. [ (✓) hoa:511 ]
|
PDF
WRAP-The-DAPA‐DIET-study-metabolic-Dapagliflozin-dietary-22.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1557Kb) | Preview |
Official URL: https://doi.org/10.1002/edm2.381
Abstract
The cardio-renal benefits of sodium glucose-like transporter 2 inhibitor (SGLT2i) therapies have been demonstrated in patients with and without type 2 diabetes. However, no studies have explored the long-term metabolic effects of SGLT2i, combined with dietary carbohydrate restriction. Our primary objective was to describe long-term changes in weight, energy expenditure, appetite and body composition after 12 months of Dapagliflozin therapy, with carbohydrate restriction, in people with type 2 diabetes and obesity. Our secondary objective was to assess changes in adiponectin and leptin.
| Item Type: | Journal Article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine R Medicine > RM Therapeutics. Pharmacology |
||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||||||
| Library of Congress Subject Headings (LCSH): | Type 2 diabetes, Type 2 diabetes -- Diet therapy, Type 2 diabetes -- Treatment, Obesity , Reducing diets , Obesity -- Treatment | ||||||||
| Journal or Publication Title: | Endocrinology, Diabetes & Metabolism | ||||||||
| Publisher: | John Wiley & Sons | ||||||||
| ISSN: | 2398-9238 | ||||||||
| Official Date: | November 2022 | ||||||||
| Dates: |
|
||||||||
| Volume: | 5 | ||||||||
| Number: | 6 | ||||||||
| Article Number: | e381 | ||||||||
| DOI: | 10.1002/edm2.381 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||
| Date of first compliant deposit: | 1 November 2022 | ||||||||
| Date of first compliant Open Access: | 1 November 2022 | ||||||||
| RIOXX Funder/Project Grant: |
|
||||||||
| Related URLs: |
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
Downloads
Downloads per month over past year
