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Photocontrolled nucleobase binding to an organometallic Ru-II arene complex
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Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha and Sadler, P. J. (2009) Photocontrolled nucleobase binding to an organometallic Ru-II arene complex. Chemical Communications (No.43). pp. 6622-6624. doi:10.1039/b914153g ISSN 1359-7345.
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Official URL: http://dx.doi.org/10.1039/b914153g
Abstract
The complex [(p-cym)Ru(bpm)(py)][PF6](2) (where p-cym = para-cymene, bpm = 2,2'-bipyrimidine and py = pyridine) is the first ruthenium(II) arene complex that can selectively photodissociate a monodentate ligand (py) when excited with visible light and form a reactive aqua derivative able to bind to a DNA base.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry Q Science > QP Physiology R Medicine > RS Pharmacy and materia medica |
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Library of Congress Subject Headings (LCSH): | Ruthenium compounds -- Therapeutic use, Aromatic compounds -- Therapeutic use, Organometallic compounds -- Therapeutic use, Antineoplastic agents, DNA-ligand interactions, Photochemistry | ||||
Journal or Publication Title: | Chemical Communications | ||||
Publisher: | Royal Society of Chemistry | ||||
ISSN: | 1359-7345 | ||||
Official Date: | 21 November 2009 | ||||
Dates: |
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Number: | No.43 | ||||
Number of Pages: | 3 | ||||
Page Range: | pp. 6622-6624 | ||||
DOI: | 10.1039/b914153g | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Funder: | Consejo Nacional de Ciencia y Tecnología (Mexico) (CONACYT), Seventh Framework Programme (European Commission) (FP7), European Regional Development Fund (ERDF), Advantage West Midlands (AWM), Overseas Research Students Awards Scheme (ORSAS) | ||||
Grant number: | 220281 (FP7) |
Data sourced from Thomson Reuters' Web of Knowledge
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