Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha and Sadler, P. J. (2009) Photocontrolled nucleobase binding to an organometallic Ru-II arene complex. Chemical Communications (No.43). pp. 6622-6624. doi:10.1039/b914153g

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Abstract

The complex [(p-cym)Ru(bpm)(py)][PF6](2) (where p-cym = para-cymene, bpm = 2,2'-bipyrimidine and py = pyridine) is the first ruthenium(II) arene complex that can selectively photodissociate a monodentate ligand (py) when excited with visible light and form a reactive aqua derivative able to bind to a DNA base.

Item Type:	Journal Article
Subjects:	Q Science > QD Chemistry Q Science > QP Physiology R Medicine > RS Pharmacy and materia medica
Divisions:	Faculty of Science > Chemistry
Library of Congress Subject Headings (LCSH):	Ruthenium compounds -- Therapeutic use, Aromatic compounds -- Therapeutic use, Organometallic compounds -- Therapeutic use, Antineoplastic agents, DNA-ligand interactions, Photochemistry
Journal or Publication Title:	Chemical Communications
Publisher:	Royal Society of Chemistry
ISSN:	1359-7345
Official Date:	21 November 2009
Dates:	Date Event 21 November 2009 Published
Number:	No.43
Number of Pages:	3
Page Range:	pp. 6622-6624
DOI:	10.1039/b914153g
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Consejo Nacional de Ciencia y Tecnología (Mexico) (CONACYT), Seventh Framework Programme (European Commission) (FP7), European Regional Development Fund (ERDF), Advantage West Midlands (AWM), Overseas Research Students Awards Scheme (ORSAS)
Grant number:	220281 (FP7)

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