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European Registry of Cardiac Arrest – Study-THREE (EuReCa THREE) – an international, prospective, multi-centre, three-month survey of epidemiology, treatment and outcome of patients with out-of-hospital cardiac arrest in Europe – the study protocol

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Wnent, Jan, Masterson, Siobhán, Maurer, Holger, Tjelmeland, Ingvild , Herlitz, Johan, Rosell Ortiz, Fernando, Kurbach, Esther, Bossaert, Leo, Perkins, Gavin and Gräsner, Jan-Thorsten (2022) European Registry of Cardiac Arrest – Study-THREE (EuReCa THREE) – an international, prospective, multi-centre, three-month survey of epidemiology, treatment and outcome of patients with out-of-hospital cardiac arrest in Europe – the study protocol. Resuscitation Plus, 12 . 100314. doi:10.1016/j.resplu.2022.100314 ISSN 2666-5204.

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Official URL: http://dx.doi.org/10.1016/j.resplu.2022.100314

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Abstract

Background
The aim of the European Registry of Cardiac Arrest (EuReCa) network is to provide high quality evidence on epidemiology of out-of-hospital cardiac arrest (OHCA) in Europe by supporting and developing cardiac arrest registries and performing European-wide studies. To date, the EuReCa ONE and EuReCa TWO studies have involved around 28 countries, with population covered increasing from the first to the second study. The aim of the EuReCa THREE study is to build on previous work and to support the promotion of quality data collection on OHCA throughout Europe.

Methods/design
EuReCa THREE will be the third prospective cohort study on epidemiology of OHCA and will involve around 30 European countries. The study will be conducted between 1st September and 30th November 2022. Data will be collected on cardiac arrest cases attended, resuscitation attempted, patient and cardiac arrest event characteristics and outcomes (including return of spontaneous circulation, status on hospital arrival and discharge). A particular focus for EuReCa THREE will be to describe key time intervals in OHCA management; time from call to EMS arrival on scene, time from cardiac arrest to start CPR, time from EMS arrival to delivery of patient to hospital.

EuReCa THREE was registered with the German Registry of Clinical Trials Registration Number: DRKS00028591 searchable via WHO meta-registry (https://apps.who.int/trialsearch/).

Discussion
The EuReCa THREE study will increase our knowledge on longitudinal OHCA epidemiology and provide new knowledge on crucial time intervals in OHCA management in Europe. However, the primary aim of building a network to support quality data on OHCA, remains the central tenant of the EuReCa project.

Item Type: Journal Article
Subjects: R Medicine > RA Public aspects of medicine
R Medicine > RC Internal medicine
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Cardiac arrest , Heart -- Diseases, Heart -- Diseases -- Patients -- Rehabilitation, Heart failure -- Patients -- Rehabilitation, Cardiac resuscitation, Heart -- Diseases -- Epidemiology
Journal or Publication Title: Resuscitation Plus
Publisher: Elsevier
ISSN: 2666-5204
Official Date: December 2022
Dates:
DateEvent
December 2022Published
6 October 2022Available
21 September 2022Accepted
6 September 2022Submitted
Volume: 12
Number of Pages: 6
Article Number: 100314
DOI: 10.1016/j.resplu.2022.100314
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 25 October 2022
Date of first compliant Open Access: 25 October 2022
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
UNSPECIFIED[NIHR] National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
UNSPECIFIEDGerman Resuscitation Councilhttp://viaf.org/viaf/127744248
UNSPECIFIEDLaerdal Foundation for Acute Medicinehttp://viaf.org/viaf/107145970152832251297

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