Weynberg, Karen Dawn, Allen, Michael J., Ashelford, Kevin, Scanlan, David J. and Wilson, William H. (2009) From small hosts come big viruses: the complete genome of a second Ostreococcus tauri virus, OtV-1. Environmental Microbiology, Vol.11 (No.11). pp. 2821-2839. ISSN 1462-2912

Full text not available from this repository.

Abstract

Ostreococcus tauri virus (OtV-1) is a large double-stranded DNA virus and a prospective member of the family Phycodnaviridae, genus Prasinovirus. OtV-1 infects the unicellular marine green alga O. tauri, the smallest known free-living eukaryote. Here we present the 191 761 base pair genome sequence of OtV-1, which has 232 putative protein-encoding and 4 tRNA-encoding genes. Approximately 31% of the viral gene products exhibit a similarity to proteins of known functions in public databases. These include a variety of unexpected genes, for example, a PhoH-like protein, a N-myristoyltransferase, a 3-dehydroquinate synthase, a number of glycosyltransferases and methyltransferases, a prolyl 4-hydroxylase, 6-phosphofructokinase and a total of 8 capsid proteins. A total of 11 predicted genes share homology with genes found in the Ostreococcus host genome. In addition, an intein was identified in the DNA polymerase gene of OtV-1. This is the first report of an intein in the genome of a virus that infects O. tauri. Fifteen core genes common to nuclear-cytoplasmic large dsDNA virus (NCLDV) genomes were identified in the OtV-1 genome. This new sequence data may help to redefine the classification of the core genes of these viruses and shed new light on their evolutionary history.

Item Type:	Journal Item
Subjects:	Q Science > QR Microbiology
Divisions:	Faculty of Science > Life Sciences (2010- ) > Biological Sciences ( -2010)
Journal or Publication Title:	Environmental Microbiology
Publisher:	Blackwell
ISSN:	1462-2912
Official Date:	November 2009
Volume:	Vol.11
Number:	No.11
Number of Pages:	19
Page Range:	pp. 2821-2839
Identification Number:	10.1111/j.1462-2920.2009.01991.x
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	National Science Foundation, Alfred P. Sloan Foundation, Genome Institute of Singapore (GIS), NHGRI
Grant number:	MCB-0701984, BR-4772, R01 HG004456-01, R01HG003521-01
URI:	http://wrap.warwick.ac.uk/id/eprint/17055

Data sourced from Thomson Reuters' Web of Knowledge

Request changes or add full text files to a record

Actions (login required)

View Item