The Library
Procalcitonin-guided use of antibiotics in acute pancreatitis – Authors' reply
Tools
Tools
Tools
Siriwardena, Ajith K., Jegatheeswaran, Santhalingam and Mason, James (2022) Procalcitonin-guided use of antibiotics in acute pancreatitis – Authors' reply. The Lancet Gastroenterology & Hepatology, 7 (12). 1074. doi:10.1016/S2468-1253(22)00332-6
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1016/S2468-1253(22)00332-6
Abstract
We thank Bilal Ahmad Mir and colleagues and Jayanta Samanta and Jahnvi Dhar for their interest in our study. 1 First, in relation to whether to restrict the procalcitonin assay to patients with moderate or severe acute pancreatitis, there is evidence of misuse of antibiotics regardless of disease severity and globally across health-care systems. 2 Furthermore, current definitions of severe disease require persistent organ dysfunction after 48 h of treatment and final allocated severity might not be apparent at presentation. 3 Thus, an effective algorithm should be evaluated at all severities of acute pancreatitis and from the point of hospital admission. Additionally, tertiary centres admit patients with severe disease who would have initially been admitted to smaller hospitals. These patients are often receiving antibiotics and applying the algorithm is logical so that those without proven infection and with a low procalcitonin can stop antibiotic therapy.
| Item Type: | Journal Item | ||||||
|---|---|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||
| Journal or Publication Title: | The Lancet Gastroenterology & Hepatology | ||||||
| Publisher: | Elsevier | ||||||
| ISSN: | 2468-1253 | ||||||
| Official Date: | 1 December 2022 | ||||||
| Dates: |
|
||||||
| Volume: | 7 | ||||||
| Number: | 12 | ||||||
| Article Number: | 1074 | ||||||
| DOI: | 10.1016/S2468-1253(22)00332-6 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
