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Comparative evaluation of the health utilities index mark 3 and the short form 6D : evidence from an individual participant data meta-analysis of very preterm and very low birthweight adults
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Bolbocean, Corneliu, Anderson, Peter J., Bartmann, Peter, Cheong, Jeanie L. Y., Doyle, Lex W., Wolke, Dieter and Petrou, Stavros (2023) Comparative evaluation of the health utilities index mark 3 and the short form 6D : evidence from an individual participant data meta-analysis of very preterm and very low birthweight adults. Quality of Life Research, 32 . 1703-1716 . doi:10.1007/s11136-023-03344-x ISSN 0962-9343.
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Official URL: http://doi.org/10.1007/s11136-023-03344-x
Abstract
Background
The most appropriate preference-based health-related quality of life (HRQoL) instruments for trials or research studies that ascertain the consequences of individuals born very preterm and/or low birthweight (VP/VLBW) are not known. Agreement between the HUI3 and SF-6D multi-attribute utility measures have not been previously investigated for VP/VLBW and normal birthweight or term-born controls. This study examined the agreement between the outputs of the HUI3 and SF-6D measures among adults born VP/VLBW and normal birthweight or term born controls.
Methods
We used two prospective cohorts of individuals born VP/VLBW and controls contributing to the ‘Research on European Children and Adults Born Preterm’ (RECAP) consortium which assessed HRQoL using two preference-based measures. The combined dataset of individual participant data (IPD) included 407 adult VP/VLBW survivors and 367 controls, ranging in age from 18 to 26 years. Bland–Altman plots, intra-class correlation coefficients, and generalized linear mixed models in a one-step approach were used to examine agreement between the measures.
Results
There was significant discordance between the HUI3 and SF-6D multi-attribute utility measures in the VP/VLBW sample, controls, and in the combined samples. Agreement between the HUI3 and SF-6D multi-attribute utility measures was weaker in controls compared with VP/VLBW individuals.
Conclusions and relevance
The HUI3 and SF-6D each provide unique information on different aspects of health status across the groups. The HUI3 better captures preterm-related changes to HRQoL in adulthood compared to SF-6D. Studies focused on measuring physical or cognitive aspects of health will likely benefit from using the HUI3 instead of the SF-6D, regardless of gestational age at birth and birthweight status.
Item Type: | Journal Article | |||||||||||||||
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Subjects: | H Social Sciences > HN Social history and conditions. Social problems. Social reform R Medicine > RA Public aspects of medicine R Medicine > RJ Pediatrics |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Science > Psychology Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | Quality of life -- Children -- Health aspects, Health status indicators, Prematurely born children, Premature infants, Birth weight, Low | |||||||||||||||
Journal or Publication Title: | Quality of Life Research | |||||||||||||||
Publisher: | Springer Netherlands | |||||||||||||||
ISSN: | 0962-9343 | |||||||||||||||
Official Date: | June 2023 | |||||||||||||||
Dates: |
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Volume: | 32 | |||||||||||||||
Page Range: | 1703-1716 | |||||||||||||||
DOI: | 10.1007/s11136-023-03344-x | |||||||||||||||
Status: | Peer Reviewed | |||||||||||||||
Publication Status: | Published | |||||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | |||||||||||||||
Date of first compliant deposit: | 1 February 2023 | |||||||||||||||
Date of first compliant Open Access: | 1 February 2023 | |||||||||||||||
RIOXX Funder/Project Grant: |
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