Salt and cardiovascular disease
Cappuccio, Francesco. (2007) Salt and cardiovascular disease. BMJ, Vol.334 . pp. 859-860. ISSN 0959-535X
WRAP_Cappuccio_0482983-061008-BMJ_2007_Salt_editorial.pdf - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Official URL: http://dx.doi.org/10.1136/bmj.39175.364954.BE
Blood pressure is the most powerful predictor of stroke and other cardiovascular events. The importance of salt (sodium chloride) intake in determining blood pressure and the incidence of hypertension is well established. Furthermore, randomised controlled clinical trials of moderate reductions in salt intake show a dose dependent cause-effect relation and lack of a threshold effect within usual levels of salt intake in populations worldwide. The effect is independent of age, sex, ethnic origin, baseline blood pressure, and body mass.
Prospective studies,2 3 4 5 with one exception,6 also indicate that higher salt intake predicts the incidence of cardiovascular events. While widespread support exists for reducing salt intake to prevent cardiovascular disease, the lack of large and long randomised trials on the effects of salt reduction on clinical outcomes has encouraged some people to argue against a policy of salt reduction in populations.
|Item Type:||Journal Article|
|Subjects:||R Medicine > R Medicine (General)
R Medicine > RC Internal medicine
|Divisions:||Faculty of Medicine > Warwick Medical School|
|Library of Congress Subject Headings (LCSH):||Cardiovascular system -- Diseases, Hypertension, Salt|
|Journal or Publication Title:||BMJ|
|Publisher:||BMJ Publishing Group Ltd.|
|Official Date:||27 April 2007|
|Page Range:||pp. 859-860|
|Access rights to Published version:||Open Access|
1 He FJ, MacGregor GA. How far should salt intake be reduced? Hypertension 2003;42:1093-9.
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