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Nucleotide sequence of the genes encoding the matrix and small hydrophobic proteins of pneumonia virus of mice

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UNSPECIFIED (1997) Nucleotide sequence of the genes encoding the matrix and small hydrophobic proteins of pneumonia virus of mice. VIRUS RESEARCH, 48 (1). pp. 27-33. ISSN 0168-1702

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Abstract

The nucleotide sequences of the genes encoding the matrix (M) protein and the small hydrophobic (SH) protein of pneumonia virus of mice (PVM) are described. The matrix protein gene contains a large open reading frame encoding polypeptide of 257 residues which shows considerable (38.6-42.1%) amino acid identity with the matrix proteins of other pneumoviruses. The matrix gene also contains a second, smaller, open reading frame (ORF) as seen with the equivalent genes of other pneumoviruses. The PVM second open reading frame is capable of encoding a polypeptide of 46 residues and shows no significant similarity with the proteins encoded by the equivalent open reading frames of the other pneumoviruses. The gene adjacent to that encoding the matrix protein encodes a small, 92 residue, polypeptide which has a central hydrophobic domain and is structurally similar to the small hydrophobic protein of respiratory syncytial virus. (C) 1997 Elsevier Science B.V.

Item Type: Journal Article
Subjects: Q Science > QR Microbiology > QR355 Virology
Journal or Publication Title: VIRUS RESEARCH
Publisher: ELSEVIER SCIENCE BV
ISSN: 0168-1702
Date: April 1997
Volume: 48
Number: 1
Number of Pages: 7
Page Range: pp. 27-33
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/17847

Data sourced from Thomson Reuters' Web of Knowledge

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