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Pertussis immunisation strategies to optimise infant pertussis control : a narrative systematic review
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Tessier, Elise, Newport, Daniel, Tran, Anh, Nash, Sophie G., Mensah, Anna A., Yun Wang, Tian, Shantikumar, Saran, Campbell, Helen, Amirthalingam, Gayatri and Todkill, Daniel (2023) Pertussis immunisation strategies to optimise infant pertussis control : a narrative systematic review. Vaccine, 41 (41). pp. 5957-5964. doi:10.1016/j.vaccine.2023.08.073 ISSN 0264-410X.
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Official URL: http://doi.org/10.1016/j.vaccine.2023.08.073
Abstract
Objective
Countries routinely offering acellular pertussis vaccine, where long-term protection is not sustained, have the challenge of selecting an optimal schedule to minimise disease among young infants. We conducted a narrative systematic review and synthesis of information to evaluate different pertussis immunisation strategies at controlling pertussis disease, hospitalisation, deaths, and vaccine effectiveness among young infants.
Methods
We conducted a review of the literature on studies about the primary, booster, and/or maternal vaccination series and synthesised findings narratively. Countries offering the first three doses of vaccine within six-months of life and a booster on or before the second year or life were defined as accelerated primary and booster schedules, respectively. Countries offering primary and booster doses later were defined as extended primary and booster schedules. All search results were screened, and articles reviewed and reconciled, by two authors. The Risk of Bias in Non-randomised Studies of Intervention tool was used to evaluate the risk of bias.
Findings
A total of 98 studies were included in the analyses and the following recurring themes were described: timing of vaccination, vaccine coverage, waning immunity/vaccine effectiveness, direct and indirect effectiveness, switching from an accelerated to extended schedule, impact of changes in testing. The risk of bias was generally low to moderate for most studies.
Conclusion
Comparing schedules is challenging and there was insufficient evidence to that one schedule was superior to another. Countries must select a schedule that maintains high vaccine coverage and reduced the risk of delaying the delivery vaccines to protect infants.
Item Type: | Journal Article | ||||||||
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Subjects: | R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||
Library of Congress Subject Headings (LCSH): | Whooping cough, Whooping cough -- Vaccination | ||||||||
Journal or Publication Title: | Vaccine | ||||||||
Publisher: | Elsevier Ltd. | ||||||||
ISSN: | 0264-410X | ||||||||
Official Date: | 22 September 2023 | ||||||||
Dates: |
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Volume: | 41 | ||||||||
Number: | 41 | ||||||||
Page Range: | pp. 5957-5964 | ||||||||
DOI: | 10.1016/j.vaccine.2023.08.073 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||
Date of first compliant deposit: | 1 September 2023 | ||||||||
Date of first compliant Open Access: | 4 September 2023 | ||||||||
RIOXX Funder/Project Grant: |
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