The Library
Increasing the versatility of the biphenyl-fused-dioxacyclodecyne class of strained alkynes
Tools
Forshaw, Sam, Parker, Jeremy S., Scott, William T., Knighton, Richard C., Tiwari, Neelam, Oladeji, Samson M., Stevens, Andrew C., Chew, Yean Ming, Reber, Jami, Clarkson, Guy J., Balasubramanian, Mohan K. and Wills, Martin (2024) Increasing the versatility of the biphenyl-fused-dioxacyclodecyne class of strained alkynes. Organic & Biomolecular Chemistry, 22 (3). pp. 590-605. doi:10.1039/d3ob01712e ISSN 1477-0539.
|
PDF
d3ob01712e.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution. Download (1436Kb) | Preview |
Official URL: https://doi.org/10.1039/d3ob01712e
Abstract
Biphenyl-fused-dioxacyclodecynes are a promising class of strained alkyne for use in Cu-free ‘click’ reactions. In this paper, a series of functionalised derivatives of this class of reagent, containing fluorescent groups, are described. Studies aimed at understanding and increasing the reactivity of the alkynes are also presented, together with an investigation of the bioconjugation of the reagents with an azide-labelled protein.
Item Type: | Journal Article | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry | |||||||||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences Faculty of Science, Engineering and Medicine > Science > Chemistry Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
|||||||||||||||
SWORD Depositor: | Library Publications Router | |||||||||||||||
Library of Congress Subject Headings (LCSH): | Chemistry, Organic, Bioconjugates, Alkynes, Chemical reactions, Catalysis | |||||||||||||||
Journal or Publication Title: | Organic & Biomolecular Chemistry | |||||||||||||||
Publisher: | The Royal Society of Chemistry | |||||||||||||||
ISSN: | 1477-0539 | |||||||||||||||
Official Date: | 21 January 2024 | |||||||||||||||
Dates: |
|
|||||||||||||||
Volume: | 22 | |||||||||||||||
Number: | 3 | |||||||||||||||
Page Range: | pp. 590-605 | |||||||||||||||
DOI: | 10.1039/d3ob01712e | |||||||||||||||
Status: | Peer Reviewed | |||||||||||||||
Publication Status: | Published | |||||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | |||||||||||||||
Date of first compliant deposit: | 16 January 2024 | |||||||||||||||
Date of first compliant Open Access: | 18 January 2024 | |||||||||||||||
RIOXX Funder/Project Grant: |
|
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year