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Glycosidase-catalysed synthesis of oligosaccharides: Trisaccharides with the alpha-D-Gal-(1->3)-D-Gal terminus responsible for the hyperacute rejection response in cross-species transplant rejection from pigs to man

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UNSPECIFIED (1996) Glycosidase-catalysed synthesis of oligosaccharides: Trisaccharides with the alpha-D-Gal-(1->3)-D-Gal terminus responsible for the hyperacute rejection response in cross-species transplant rejection from pigs to man. CHEMICAL COMMUNICATIONS (12). pp. 1473-1474. ISSN 1359-7345

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Abstract

alpha-Galactosidases from Coffea arabica, Aspergillus niger and A. oryzae catalyse the transfer of alpha-galactosyl residues on to lactose thioglycosides to give 1 --> 3 and 1 --> 6 linked trisaccharides, including an unusual branched trisaccharide 11 and the isoglobotriose glycoside 4, which, as 'linear B type 6', has been recognised as of the type responsible for the hyperacute rejection response in pig-to-man xenotransplantation.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Journal or Publication Title: CHEMICAL COMMUNICATIONS
Publisher: ROYAL SOC CHEMISTRY
ISSN: 1359-7345
Date: 21 June 1996
Number: 12
Number of Pages: 2
Page Range: pp. 1473-1474
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/18611

Data sourced from Thomson Reuters' Web of Knowledge

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