Flash chiral chromatography with cellulose tris(3,5-dimethylphenylcarbamate)-coated phases Improved resolution of basic analytes
UNSPECIFIED (1996) Flash chiral chromatography with cellulose tris(3,5-dimethylphenylcarbamate)-coated phases Improved resolution of basic analytes. In: 19th International Symposium on Column Liquid Chromatography, INNSBRUCK, AUSTRIA, MAY 28-JUN 02, 1995. Published in: JOURNAL OF CHROMATOGRAPHY A, 728 (1-2). pp. 195-199.Full text not available from this repository.
The preparative resolution of some chiral basic analytes on a flash chiral chromatography column packed with a cellulose carbamate-coated phase is described. Compared with separations obtained, on a column packed with 20% (w/w) cellulose tris(3,5-dimethylphenylcarbamate) coated onto underivatised flash silica (40-63 mu m Davisil, 150 Angstrom), a substantial improvement was observed when the support medium was changed to octadecylated silica (37-55 mu m Bondapak ODS, 300 Angstrom). The ODS phase is extremely effective for the preparative separation of basic analytes such as beta-blockers and the optimum conditions can be readily established by the use of a related high-pressure liquid chromatography column containing the chiral carbamate coated onto Nucleosil-ODS (5 mu m, 300 Angstrom).
|Item Type:||Conference Item (UNSPECIFIED)|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||JOURNAL OF CHROMATOGRAPHY A|
|Publisher:||ELSEVIER SCIENCE BV|
|Official Date:||29 March 1996|
|Number of Pages:||5|
|Page Range:||pp. 195-199|
|Title of Event:||19th International Symposium on Column Liquid Chromatography|
|Location of Event:||INNSBRUCK, AUSTRIA|
|Date(s) of Event:||MAY 28-JUN 02, 1995|
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