UNSPECIFIED (1996) Carbohydrate carbamate coated onto microporous silica: Application to chiral analysis of commercial pharmaceutical drugs. In: 6th International Symposium on Chiral Discrimination, APR 26-28, 1995, ST LOUIS, MO.

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Abstract

The enantioselectivity of a series of chiral analytes was examined on tris-(3,5-dimethylphenyl carbamate) coated onto microporous APS-silica. The effects of the nature of the carbohydrate, the weight ratio of carbamate/support and the type of alcohol present in the mobile phase were investigated. Among the chiral analytes examined, propanolol showed an extremely good resolution. The resolution of tetramisole was optimized and the method developed was shown to be suitable for analysis of the drug in commercial tablets and in a suspension. (C) 1996 Wiley-Liss, Inc.

Item Type:	Conference Item (UNSPECIFIED)
Subjects:	Q Science > QD Chemistry R Medicine > RS Pharmacy and materia medica
Journal or Publication Title:	CHIRALITY
Publisher:	WILEY-LISS
ISSN:	0899-0042
Date:	1996
Volume:	8
Number:	1
Number of Pages:	4
Page Range:	pp. 143-146
Publication Status:	Published
Title of Event:	6th International Symposium on Chiral Discrimination
Location of Event:	ST LOUIS, MO
Date(s) of Event:	APR 26-28, 1995
URI:	http://wrap.warwick.ac.uk/id/eprint/19017

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