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SEQUENCE AND IN-VITRO EXPRESSION OF THE PHOSPHOPROTEIN GENE OF AVIAN PNEUMOVIRUS
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UNSPECIFIED (1995) SEQUENCE AND IN-VITRO EXPRESSION OF THE PHOSPHOPROTEIN GENE OF AVIAN PNEUMOVIRUS. VIRUS RESEARCH, 36 (2-3). pp. 247-257.
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Abstract
The phosphoprotein (P) gene of two subgroup A strains of avian pneumovirus comprised 855 nucleotides containing only one substantial open reading frame encoding a protein of 278 amino acids, with a predicted M(r) of 30,323. In vitro translation of P mRNA in a wheat germ system resulted in the synthesis of two polypeptides of M(r) 35,000. Comparison of the deduced P protein sequence with that of the known mammalian pneumoviruses revealed overall amino acid identities ranging from 31 to 34.5%, suggesting a distant relationship. However, there was a much higher identity (63.2-68.4%) in a region of 57 residues, which included a heptad repeat sequence.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | Q Science > QR Microbiology > QR355 Virology | ||||
| Journal or Publication Title: | VIRUS RESEARCH | ||||
| Publisher: | ELSEVIER SCIENCE BV | ||||
| ISSN: | 0168-1702 | ||||
| Official Date: | May 1995 | ||||
| Dates: |
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| Volume: | 36 | ||||
| Number: | 2-3 | ||||
| Number of Pages: | 11 | ||||
| Page Range: | pp. 247-257 | ||||
| Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
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