UNSPECIFIED (1995) SEQUENCE AND IN-VITRO EXPRESSION OF THE PHOSPHOPROTEIN GENE OF AVIAN PNEUMOVIRUS. VIRUS RESEARCH, 36 (2-3). pp. 247-257. ISSN 0168-1702

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Abstract

The phosphoprotein (P) gene of two subgroup A strains of avian pneumovirus comprised 855 nucleotides containing only one substantial open reading frame encoding a protein of 278 amino acids, with a predicted M(r) of 30,323. In vitro translation of P mRNA in a wheat germ system resulted in the synthesis of two polypeptides of M(r) 35,000. Comparison of the deduced P protein sequence with that of the known mammalian pneumoviruses revealed overall amino acid identities ranging from 31 to 34.5%, suggesting a distant relationship. However, there was a much higher identity (63.2-68.4%) in a region of 57 residues, which included a heptad repeat sequence.

Item Type:	Journal Article
Subjects:	Q Science > QR Microbiology > QR355 Virology
Journal or Publication Title:	VIRUS RESEARCH
Publisher:	ELSEVIER SCIENCE BV
ISSN:	0168-1702
Date:	May 1995
Volume:	36
Number:	2-3
Number of Pages:	11
Page Range:	pp. 247-257
Publication Status:	Published
URI:	http://wrap.warwick.ac.uk/id/eprint/19830

Data sourced from Thomson Reuters' Web of Knowledge

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