UNSPECIFIED. (1995) SEQUENCE AND IN-VITRO EXPRESSION OF THE PHOSPHOPROTEIN GENE OF AVIAN PNEUMOVIRUS. VIRUS RESEARCH, 36 (2-3). pp. 247-257. ISSN 0168-1702

Abstract

The phosphoprotein (P) gene of two subgroup A strains of avian pneumovirus comprised 855 nucleotides containing only one substantial open reading frame encoding a protein of 278 amino acids, with a predicted M(r) of 30,323. In vitro translation of P mRNA in a wheat germ system resulted in the synthesis of two polypeptides of M(r) 35,000. Comparison of the deduced P protein sequence with that of the known mammalian pneumoviruses revealed overall amino acid identities ranging from 31 to 34.5%, suggesting a distant relationship. However, there was a much higher identity (63.2-68.4%) in a region of 57 residues, which included a heptad repeat sequence.

Data sourced from Thomson Reuters' Web of Knowledge

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