UNSPECIFIED. (1994) THE DEVELOPMENT AND VALIDATION OF AN AGE-STRUCTURED MODEL FOR THE EVALUATION OF DISEASE-CONTROL STRATEGIES FOR INTESTINAL HELMINTHS. PARASITOLOGY, 109 (Part 3). pp. 389-396. ISSN 0031-1820

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Abstract

Epidemiological modelling can be a useful tool for the evaluation of parasite control strategies. An age-structured epidemiological model of intestinal helminth dynamics is developed. This model includes the explicit representation of changing worm distributions between hosts as a result of treatment, and estimates the morbidity due to heavy infections. The model is used to evaluate the effectiveness of different programmes of age-targeted community chemotherapy in reducing the amount of morbidity due to helminth infection. The magnitude of age-related heterogeneities is found to be very important in determining the results of age-targeted treatment programmes. The model was verified using field data from control programmes for Ascaris lumbricoides and Trichuris is trichiura, and was found to provide accurate predictions of prevalence and mean intensities of infection during and following different control regimes.

Item Type:	Journal Article
Subjects:	Q Science > QL Zoology
Journal or Publication Title:	PARASITOLOGY
Publisher:	CAMBRIDGE UNIV PRESS
ISSN:	0031-1820
Official Date:	September 1994
Dates:	Date Event September 1994 UNSPECIFIED
Volume:	109
Number:	Part 3
Number of Pages:	8
Page Range:	pp. 389-396
Publication Status:	Published
URI:	http://wrap.warwick.ac.uk/id/eprint/20280

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