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ISOLATION OF A NOVEL RXR FROM XENOPUS THAT MOST CLOSELY RESEMBLES MAMMALIAN RXR-BETA AND IS EXPRESSED THROUGHOUT EARLY DEVELOPMENT

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UNSPECIFIED (1994) ISOLATION OF A NOVEL RXR FROM XENOPUS THAT MOST CLOSELY RESEMBLES MAMMALIAN RXR-BETA AND IS EXPRESSED THROUGHOUT EARLY DEVELOPMENT. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 1218 (3). pp. 267-272. ISSN 0167-4781

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Abstract

In a search for nuclear receptors that may mediate the teratogenic effects of the potential morphogen, retinoic acid, on the early development of Xenopus we have isolated a novel Xenopus RXR that most closely resembles the mammalian beta-type RXR. Xenopus RXR beta mRNA is expressed throughout early embryogenesis, and functions as an accessory protein to enhance the DNA-binding of other members of the nuclear receptor superfamily.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
Journal or Publication Title: BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
Publisher: ELSEVIER SCIENCE BV
ISSN: 0167-4781
Date: 2 August 1994
Volume: 1218
Number: 3
Number of Pages: 6
Page Range: pp. 267-272
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/20415

Data sourced from Thomson Reuters' Web of Knowledge

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