UNSPECIFIED (1993) NOVEL BIOACTIVE COMPOUNDS FROM ACTINOMYCETES. In: 5th European Actinomycetes Group Meeting, PASTEUR INST, PARIS, FRANCE, APR 03-04, 1993. Published in: RESEARCH IN MICROBIOLOGY, 144 (8). pp. 661-663. ISSN 0923-2508.

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Abstract

Actinomycetes form an enormous reservoir of secondary metabolites and enzymes. The potential for exploiting rare actinomycetes is highlighted by the discovery of novel compounds from strains of Spirillospora and Nocardioides. Novel compounds of well known classes of antibiotics, such as polyenes. continue to be discovered. For compounds containing a chromophore. the analysis by high-performance liquid chromatography coupled with a diode-array detector enables the elimination of producers of known compounds and facilitates the discovery of novel compounds or derivatives. The complexity of the regulatory mechanisms is illustrated by glutamine synthetase. The characterization of thermostable amylolytic, lignolytic, peroxidase and neuramidase activities, and the isolation of novel cellulolytic actinomycetes clearly demonstrate the potential of Actinomycetes as producers of enzymes.

Item Type:	Conference Item (UNSPECIFIED)
Subjects:	Q Science > QR Microbiology
Journal or Publication Title:	RESEARCH IN MICROBIOLOGY
Publisher:	EDITIONS SCIENTIFIQUES ELSEVIER
ISSN:	0923-2508
Official Date:	October 1993
Dates:	Date Event October 1993 UNSPECIFIED
Volume:	144
Number:	8
Number of Pages:	3
Page Range:	pp. 661-663
Publication Status:	Published
Title of Event:	5th European Actinomycetes Group Meeting
Location of Event:	PASTEUR INST, PARIS, FRANCE
Date(s) of Event:	APR 03-04, 1993

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