LIGHT-INDUCED CAROTENOGENESIS IN MYXOCOCCUS-XANTHUS - DNA-SEQUENCE ANALYSIS OF THE CARR REGION
UNSPECIFIED. (1993) LIGHT-INDUCED CAROTENOGENESIS IN MYXOCOCCUS-XANTHUS - DNA-SEQUENCE ANALYSIS OF THE CARR REGION. MOLECULAR MICROBIOLOGY, 10 (4). pp. 713-735. ISSN 0950-382XFull text not available from this repository.
The carR region encodes a light-inducible promoter, a negative regulator of the promoter and a trans-acting activator that controls the light-inducible Myxococcus xanthus carotenoid biosynthesis regulon. DNA sequence analysis revealed, downstream of the promoter, three translationally coupled genes, carQ, carR and carS. Sequencing of mutations demonstrated that carR encoded the negative regulator and was an integral membrane protein. Mutant construction and sequencing revealed that carS was the trans-acting activator and that carQ was a positive regulator of the promoter. Neither gene encodes proteins with known sequence-specific DNA-binding motifs. The sequence of the light-inducible promoter region, identified by primer extension analysis, showed similarity to the consensus sequence of the Escherichia coli stress response ('heat-shock') promoters.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry
Q Science > QR Microbiology
|Journal or Publication Title:||MOLECULAR MICROBIOLOGY|
|Publisher:||BLACKWELL SCIENCE LTD|
|Official Date:||November 1993|
|Number of Pages:||23|
|Page Range:||pp. 713-735|
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