Richards, Adair D. and Rodger, Alison. (2007) Synthetic metallomolecules as agents for the control of DNA structure. Chemical Society Reviews, 36 (No.3). pp. 471-483. ISSN 0306-0012

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Abstract

This tutorial review summarises B-DNA structure and metallomolecule binding modes and illustrates some DNA structures induced by molecules containing metallic cations. The effects of aquated metal ions, cobalt amines, ruthenium octahedral metal complexes, metallohelicates and platinum complexes such as cis-platin are discussed alongside the techniques of NMR, X-ray crystallography, gel electrophoresis, circular dichroism, linear dichroism and molecular dynamics. The review will be of interest to people interested in both DNA structure and roles of metallomolecules in biological systems.

Item Type:	Journal Article
Subjects:	Q Science > QD Chemistry Q Science > QR Microbiology
Divisions:	Faculty of Science > Chemistry Faculty of Science > Molecular Organisation and Assembly in Cells (MOAC)
Library of Congress Subject Headings (LCSH):	DNA -- Research, X-ray crystallography, Cations, Organometallic compounds
Journal or Publication Title:	Chemical Society Reviews
Publisher:	Royal Society of Chemistry
ISSN:	0306-0012
Date:	2007
Volume:	36
Number:	No.3
Page Range:	pp. 471-483
Identification Number:	10.1039/b609495c
Status:	Peer Reviewed
Access rights to Published version:	Open Access
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URI:	http://wrap.warwick.ac.uk/id/eprint/2189

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