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Synthetic metallomolecules as agents for the control of DNA structure
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Richards, Adair D. and Rodger, Alison (2007) Synthetic metallomolecules as agents for the control of DNA structure. Chemical Society Reviews, 36 (No.3). pp. 471-483. doi:10.1039/b609495c ISSN 0306-0012.
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Official URL: http://dx.doi.org/10.1039/b609495c
Abstract
This tutorial review summarises B-DNA structure and metallomolecule binding modes and illustrates some DNA structures induced by molecules containing metallic cations. The effects of aquated metal ions, cobalt amines, ruthenium octahedral metal complexes, metallohelicates and platinum complexes such as cis-platin are discussed alongside the techniques of NMR, X-ray crystallography, gel electrophoresis, circular dichroism, linear dichroism and molecular dynamics. The review will be of interest to people interested in both DNA structure and roles of metallomolecules in biological systems.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry Q Science > QR Microbiology |
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry Faculty of Science, Engineering and Medicine > Research Centres > Molecular Organisation and Assembly in Cells (MOAC) |
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Library of Congress Subject Headings (LCSH): | DNA -- Research, X-ray crystallography, Cations, Organometallic compounds | ||||
Journal or Publication Title: | Chemical Society Reviews | ||||
Publisher: | Royal Society of Chemistry | ||||
ISSN: | 0306-0012 | ||||
Official Date: | 2007 | ||||
Dates: |
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Volume: | 36 | ||||
Number: | No.3 | ||||
Page Range: | pp. 471-483 | ||||
DOI: | 10.1039/b609495c | ||||
Status: | Peer Reviewed | ||||
Access rights to Published version: | Open Access (Creative Commons) |
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