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A H-1-NMR METHOD FOR THE DETERMINATION OF ENANTIOMERIC EXCESS AND ABSOLUTE-CONFIGURATION OF CIS-DIHYDRODIOL METABOLITES OF POLYCYCLIC ARENES AND HETEROARENES

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UNSPECIFIED (1992) A H-1-NMR METHOD FOR THE DETERMINATION OF ENANTIOMERIC EXCESS AND ABSOLUTE-CONFIGURATION OF CIS-DIHYDRODIOL METABOLITES OF POLYCYCLIC ARENES AND HETEROARENES. TETRAHEDRON LETTERS, 33 (9). pp. 1241-1244. ISSN 0040-4039

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Abstract

Metabolism of benzofuran and 2,3-dihydrobenzofuran by P.putida UV4 each yielded cis-dihydrodiols; catalytic hydrogenation of the cis-dihydrodiols obtained from polycyclic arenes and azaarenes followed by diMTPA ester formation (using both R- and S-MTPA) on the cis-tetrahydrodiols formed the basis of a H-1-NMR method for the determination of both enantiomeric excess and absolute configuration.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Journal or Publication Title: TETRAHEDRON LETTERS
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
ISSN: 0040-4039
Date: 25 February 1992
Volume: 33
Number: 9
Number of Pages: 4
Page Range: pp. 1241-1244
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/22210

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