NMR-STUDIES OF THE FLEXIBILITY OF THE GLYCOSYL RING IN THYMIDINE AND URIDINE NUCLEOSIDES
UNSPECIFIED (1991) NMR-STUDIES OF THE FLEXIBILITY OF THE GLYCOSYL RING IN THYMIDINE AND URIDINE NUCLEOSIDES. CARBOHYDRATE RESEARCH, 216 . pp. 1-9. ISSN 0008-6215Full text not available from this repository.
H-1-N.m.r. spectroscopy at various temperatures has been used to investigate the flexibility of the glycosyl ring and to calculate the percentage of N- and S-character in the most favoured conformations in solution adopted by various pyrimidine deoxyribonucleosides. The position and orientation of substituents have a definite and predictable influence on the conformation of the deoxyribose ring in these nucleosides. The deoxyribose rings in the nucleosides studied were, in general, flexible except for those of 3'-deoxy-3'-fluoro- and 3'-azido-3'-deoxy-thymidine and 2'-deoxy-2'-fluoro-5-methyl-arabinosyluracil.
|Item Type:||Journal Article|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||CARBOHYDRATE RESEARCH|
|Publisher:||ELSEVIER SCIENCE BV|
|Date:||2 September 1991|
|Number of Pages:||9|
|Page Range:||pp. 1-9|
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