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DETERMINATION OF THE AMINO-ACID-SEQUENCE OF CYSTINE-CONTAINING PEPTIDES BY TANDEM MASS-SPECTROMETRY

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UNSPECIFIED (1991) DETERMINATION OF THE AMINO-ACID-SEQUENCE OF CYSTINE-CONTAINING PEPTIDES BY TANDEM MASS-SPECTROMETRY. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 5 (4). pp. 156-159. ISSN 0951-4198

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Abstract

A method has been developed for the determination of the amino-acid sequence of a cyclic peptide containing cystine. It is based on the reduction of the peptide in a reductive matrix prior to ionization by fast-atom bombardment. The amino-acid sequence of the resulting linear peptide is then determined by tandem mass spectrometry from the spectrum produced by the collision-induced decomposition of the [M + H]+ ion of the peptide.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Q Science > QC Physics
Journal or Publication Title: RAPID COMMUNICATIONS IN MASS SPECTROMETRY
Publisher: JOHN WILEY & SONS LTD
ISSN: 0951-4198
Date: April 1991
Volume: 5
Number: 4
Number of Pages: 4
Page Range: pp. 156-159
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/22508

Data sourced from Thomson Reuters' Web of Knowledge

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