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THE NUCLEOTIDE-SEQUENCES OF INTERGENIC REGIONS BETWEEN 9 GENES OF PNEUMONIA VIRUS OF MICE ESTABLISH THE PHYSICAL ORDER OF THESE GENES IN THE VIRAL GENOME

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UNSPECIFIED (1991) THE NUCLEOTIDE-SEQUENCES OF INTERGENIC REGIONS BETWEEN 9 GENES OF PNEUMONIA VIRUS OF MICE ESTABLISH THE PHYSICAL ORDER OF THESE GENES IN THE VIRAL GENOME. VIRUS RESEARCH, 18 (2-3). pp. 263-270. ISSN 0168-1702

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Abstract

We have cloned eight intergenic regions from the Pneumovirus pneumonia virus of mice that link the nine small and medium sized genes previously described (Chambers et al., 1990). The nucleotide sequences of the clones confirm the locations of these genes and their mRNA transcripts in the viral genome. The intergenic regions vary in size from 2-56 nucleotides and show only faint homology to each other or to their analogues in respiratory syncytial virus. Sequence alignments suggest that the location of the transcriptional start site for the mRNA encoding the major nucleocapsid protein of pneumonia virus of mice and respiratory syncytial virus may have altered during virus evolution by gain or loss of a transcriptional start signal.

Item Type: Journal Article
Subjects: Q Science > QR Microbiology > QR355 Virology
Journal or Publication Title: VIRUS RESEARCH
Publisher: ELSEVIER SCIENCE BV
ISSN: 0168-1702
Date: March 1991
Volume: 18
Number: 2-3
Number of Pages: 8
Page Range: pp. 263-270
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/22799

Data sourced from Thomson Reuters' Web of Knowledge

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