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Anxiety disorders in mothers and their children : results from a prospective-longitudinal community study

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Schreier, Andrea, Wittchen, Hans-Ulrich, Höfler, Michael and Lieb, Roselind. (2008) Anxiety disorders in mothers and their children : results from a prospective-longitudinal community study. British Journal of Psychiatry, Vol.192 (No.4). pp. 308-309. ISSN 0007-1250

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Official URL: http://dx.doi.org/10.1192/bjp.bp.106.033589

Abstract

The relationship between DSM–IV anxiety disorders and their clinical characteristics in mothers and anxiety in offspring was examined in 933 mother–child pairs from a longitudinal community study. Offspring of mothers with an anxiety disorder had an elevated risk of developing any anxiety disorder, compared with offspring of mothers with no anxiety disorder. Increased risk of anxiety in the offspring was especially associated with maternal social phobia and generalised anxiety disorder, and with maternal diagnoses of early onset, greater number and more severe impairment. These results suggest that the type of maternal anxiety disorder and its severity of manifestation contribute to mother–offspring aggregation of anxiety

Item Type: Journal Article
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine > RJ Pediatrics
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Anxiety disorders, Anxiety in children, Parent and child, Parenting
Journal or Publication Title: British Journal of Psychiatry
Publisher: Royal College of Psychiatrists
ISSN: 0007-1250
Date: April 2008
Volume: Vol.192
Number: No.4
Page Range: pp. 308-309
Identification Number: 10.1192/bjp.bp.106.033589
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: Germany. Bundesministerium für Bildung und Forschung (BMBF), Deutsche Forschungsgemeinschaft (DFG)
Grant number: 01EB9405/6 (BMBF), 01EB9901/6 (BMBF), EB01016200 (BMBF), 01EB0140 (BMBF), 01EB0440 (BMBF), LA1148/1-1 (DFG), WI2246/1-1 (DFG), WI 709/7-1 (DFG), WI 709/8-1 (DFG)
References: (1) Schreier A, Höfler M, Wittchen H-U, Lieb R. Clinical characteristics of major depressive disorder run in families - A community study of 933 mothers and their children. J Psychiatr Res 2006;40:283-92. (2) Merikangas KR. Vulnerability factors for anxiety disorders in children and adolescents. Child Adolesc Psychiatr Clin N Am 2005;14:649-79. (3) Biederman J, Petty C, Faraone SV, Hirshfeld-Becker DR, Henin A, Dougherty M et al. Parental predictors of pediatric panic disorder/agoraphobia: a controlled study in high-risk offspring. Depress Anxiety 2005;22:114-20. (4) American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). 4th ed. Washington, DC: APA; 1994. (5) Lieb R, Isensee B, von Sydow K, Wittchen H-U. The early developmental stages of psychopatholgoy study (EDSP): A methodological update. Eur Addict Res 2000;6:170-82. (6) Wittchen H-U, Perkonigg A, Lachner G, Nelson CB. Early developmental stages of psychopathology study (EDSP): Objectives and design. Eur Addict Res 1998;4:18-27. (7) Andersen PK, Keiding N. Survival analysis. In: Armitage P, David HA, editors. Advances in biometry: 50 years of the International Biometric Society.New York, NY: Wiley & Sons; 1996. p. 177-200. (8) McCullagh P, Nelder JA. Generalized linear models. 2nd ed. London: Chapman & Hall; 1989. (9) Lieb R, Isensee B, Höfler M, Pfister H, Wittchen H-U. Parental major depression and the risk of depressive and other mental disorders in offspring: A prospective-longitudinal community study. Arch Gen Psychiatry 2002;59:365-74. (10) Beidel DC, Turner SM. At risk for anxiety: I. Psychopathology in the offspring of anxious parents. J Am Acad Child Adolesc Psychiatry 1997;36:918-24. (11) Bijl RV, Cuijpers P, Smit F. Psychiatric disorders in adult children of parents with a history of psychopathology. Soc Psychiatry Psychiatr Epidemiol 2002;37:7-12. (12) Unnewehr S, Schneider S, Florin I, Margraf J. Psychopathology in children of patients with panic disorder or animal phobia. Psychopathology 1998;31:69-84. (13) Biederman J, Petty C, Hirshfeld-Becker DR, Henin A, Faraone SV, Dang D et al. A controlled longitudinal 5-year follow-up study of children at high and low risk for panic disorder and major depression. Psychol Med 2006;36:1141-52. (14) Brückl T, Wittchen H-U, Höfler M, Pfister H, Schneider S, Lieb R. Childhood separation anxiety and the risk for subsequent psychopathology: Results from a community study. Psychother Psychosom 2007;76:47-56. (15) Goldstein RB, Wickramaratne PJ, Horwath E, Weissman MM. Familial aggregation and phenomenology of 'early'-onset (at or before age 20 years) panic disorder. Arch Gen Psychiatry 1997;54:271-8.
URI: http://wrap.warwick.ac.uk/id/eprint/238

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