Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Adaptive clinical trials incorporating treatment selection and evaluation: methodology and application in progressive multiple sclerosis

Tools
- Tools
+ Tools

Nicholas, R. (Richard), Chataway, Jeremy, Todd, S. C. (Susan C.), Stallard, Nigel, Valdés-Márquez, Elsa, Parsons, Nicholas R. and Friede, Tim (2009) Adaptive clinical trials incorporating treatment selection and evaluation: methodology and application in progressive multiple sclerosis. In: 25th Congress of the European Committee for Treatment and Research in Multiple Sclerosis, Düsseldorf, Germany, 9-12th September 2009

[img]
Preview
PDF (Poster Summary)
WRAP_Stocks_ECTRIMS2009_abstract.pdf - Draft Version - Requires a PDF viewer.

Download (30Kb)
[img]
Preview
PDF (Poster)
WRAP_Stocks_ECTRIMS_2009_MS_AD.pdf - Draft Version - Requires a PDF viewer.

Download (67Kb)

Request Changes to record.

Abstract

In progressive multiple sclerosis (MS) irreversible disability often takes many years to accumulate as a result prolonged trials are required to assess the benefits of therapies. There is a need to understand the relationship between short-term outcome measures such as MRI endpoints and long-term clinical outcomes in progression to determine the evolution of the disease early on. Thus, the common phase I-II-III paradigm for clinical trial design with separate trials for each phase may not be appropriate.

Item Type: Conference Item (Poster)
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Multiple sclerosis -- Research -- Congresses, Clinical trials -- Design, Clinical trials -- Methodology, Neurology -- Congresses
Official Date: 2009
Dates:
DateEvent
2009Published
Status: Peer Reviewed
Access rights to Published version: Open Access
Adapted As: Nicholas, R. et al. (2009). Adaptive clinical trials incorporating treatment selection and evaluation: methodology and application in progressive multiple sclerosis. Multiple Sclerosis, 15(9 Suppl.), pp. S142-S143.
Conference Paper Type: Poster
Title of Event: 25th Congress of the European Committee for Treatment and Research in Multiple Sclerosis
Type of Event: Conference
Location of Event: Düsseldorf, Germany
Date(s) of Event: 9-12th September 2009

Data sourced from Thomson Reuters' Web of Knowledge

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics

twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us