Corre, Christophe and Challis, Gregory L. (2009) New natural product biosynthetic chemistry discovered by genome mining. Natural Product Reports, Vol.26 (No.8). pp. 977-986. doi:10.1039/b713024b

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Abstract

Analyses of plant and microbial genome sequences have revealed many genes and gene clusters encoding proteins similar to those known to be involved in the biosynthesis of structurally-complex natural products. Many of these genes and gene clusters do not direct the production of known metabolites of the organism in which they are found. Others represent novel gene clusters that direct the biosynthesis of known natural products. This article highlights several examples of new biosynthetic chemistry discovered in the course of investigating such gene clusters.

Item Type:	Journal Item
Subjects:	Q Science > QD Chemistry
Divisions:	Faculty of Science, Engineering and Medicine > Science > Chemistry
Journal or Publication Title:	Natural Product Reports
Publisher:	Royal Society of Chemistry
ISSN:	0265-0568
Official Date:	August 2009
Dates:	Date Event August 2009 Published
Volume:	Vol.26
Number:	No.8
Number of Pages:	10
Page Range:	pp. 977-986
DOI:	10.1039/b713024b
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC), European Union
Grant number:	B16610, EGH16081, 005224

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