Bugg, Tim (2009) Oxygenases get to grips with polypeptides. Structure, Vol.17 (No.7). pp. 913-914. ISSN 0969-2126

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Abstract

Hydroxylation of two proline residues in hypoxia inducible factor Hif-1α is a key step in the response to hypoxia. Here, Chowdury et al. (2009) elucidate the structural basis of this process by describing a structure for prolyl hydroxylase PHD2 bound to a peptide substrate.

Item Type:	Journal Item
Subjects:	Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology
Divisions:	Faculty of Science > Chemistry
Journal or Publication Title:	Structure
Publisher:	Cell Press
ISSN:	0969-2126
Official Date:	15 July 2009
Volume:	Vol.17
Number:	No.7
Number of Pages:	2
Page Range:	pp. 913-914
Identification Number:	10.1016/j.str.2009.06.004
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
URI:	http://wrap.warwick.ac.uk/id/eprint/27572

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