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Oxygenases get to grips with polypeptides
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Bugg, Tim (2009) Oxygenases get to grips with polypeptides. Structure, Vol.17 (No.7). pp. 913-914. doi:10.1016/j.str.2009.06.004
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Official URL: http://dx.doi.org/10.1016/j.str.2009.06.004
Abstract
Hydroxylation of two proline residues in hypoxia inducible factor Hif-1α is a key step in the response to hypoxia. Here, Chowdury et al. (2009) elucidate the structural basis of this process by describing a structure for prolyl hydroxylase PHD2 bound to a peptide substrate.
| Item Type: | Journal Item | ||||
|---|---|---|---|---|---|
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology |
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| Divisions: | Faculty of Science > Chemistry | ||||
| Journal or Publication Title: | Structure | ||||
| Publisher: | Cell Press | ||||
| ISSN: | 0969-2126 | ||||
| Official Date: | 15 July 2009 | ||||
| Dates: |
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| Volume: | Vol.17 | ||||
| Number: | No.7 | ||||
| Number of Pages: | 2 | ||||
| Page Range: | pp. 913-914 | ||||
| DOI: | 10.1016/j.str.2009.06.004 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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