Motor and executive function at 6 years of age after extremely preterm birth
Marlow, Neil, Hennessy, Enid M., Bracewell, Melanie A. and Wolke, Dieter. (2007) Motor and executive function at 6 years of age after extremely preterm birth. Pediatrics, Vol.120 (No.4). pp. 793-804. ISSN 0031-4005
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Official URL: http://dx.doi.org/10.1542/peds.2007-0440
BACKGROUND. Studies of very preterm infants have demonstrated impairments in multiple neurocognitive domains. We hypothesized that neuromotor and executive-
function deficits may independently contribute to school failure.
METHODS.We studied children who were born at 25 completed weeks’ gestation in the United Kingdom and Ireland in 1995 at early school age. Children underwent
standardized cognitive and neuromotor assessments, including the Kaufman Assessment Battery for Children and NEPSY, and a teacher-based assessment of academic achievement.
RESULTS. Of 308 surviving children, 241 (78%) were assessed at a median age of 6 years 4 months. Compared with 160 term classmates, 180 extremely preterm children without cerebral palsy and attending mainstream school performed less
well on 3 simple motor tasks: posting coins, heel walking, and 1-leg standing. They more frequently had non–right-hand preferences (28% vs 10%) and more associated/
overflow movements during motor tasks. Standardized scores for visuospatial and sensorimotor function performance differed from classmates by 1.6 and 1.1 SDs of the classmates’ scores, respectively. These differences attenuated but remained significant after controlling for overall cognitive scores. Cognitive, visuospatial
scores, and motor scores explained 54% of the variance in teachers’ ratings of performance in the whole set; in the extremely preterm group, additional variance was explained by attention-executive tasks and gender.
CONCLUSIONS. Impairment of motor, visuospatial, and sensorimotor function, including planning, self-regulation, inhibition, and motor persistence, contributes excess
morbidity over cognitive impairment in extremely preterm children and contributes independently to poor classroom performance at 6 years of age.
|Item Type:||Journal Article|
|Subjects:||R Medicine > RJ Pediatrics|
|Divisions:||Faculty of Medicine > Warwick Medical School|
|Library of Congress Subject Headings (LCSH):||Child development, Premature infants, Neuropsychology|
|Journal or Publication Title:||Pediatrics|
|Publisher:||American Academy of Pediatrics|
|Official Date:||1 October 2007|
|Page Range:||pp. 793-804|
|Access rights to Published version:||Open Access|
|Funder:||BLISS (Organisation), Health Foundation (Great Britain) (HF), WellBeing (Organization)|
1. Wood NS, Marlow N, Costeloe K, Gibson AT, Wilkinson AR.
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