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In vitro biosynthesis of bacterial peptidoglycan using D-Cys-containing precursors : fluorescent detection of transglycosylation and transpeptidation

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Vinatier, Virginie, Blakey, Carl B., Braddick, Darren, Johnson, Benjamin R. G., Evans, Stephen D. and Bugg, Tim. (2009) In vitro biosynthesis of bacterial peptidoglycan using D-Cys-containing precursors : fluorescent detection of transglycosylation and transpeptidation. Chemical Communications (No.27). pp. 4037-4039. ISSN 1359-7345

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Official URL: http://dx.doi.org/10.1039/b819869a

Abstract

Peptidoglycan precursors containing D-Cys at position 4 were polymerised to form a synthetic peptidoglycan layer, which could be fluorescently labelled, providing a new method to monitor peptidoglycan transglycosylation and transpeptidation.

Item Type:

Journal Article

Subjects:

Q Science > QD Chemistry
Q Science > QP Physiology

Divisions:

Faculty of Science > Chemistry

Library of Congress Subject Headings (LCSH):

Peptidoglycans -- Synthesis, Transpeptidation, Antibacterial agents, Polymerization

Journal or Publication Title:

Chemical Communications

Publisher:

Royal Society of Chemistry

ISSN:

1359-7345

Official Date:

2009

Dates:

Date	Event
2009	Published

Number:

No.27

Number of Pages:

Page Range:

pp. 4037-4039

Identification Number:

10.1039/b819869a

Status:

Peer Reviewed

Publication Status:

Published

References:

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