The Library

In vitro biosynthesis of bacterial peptidoglycan using D-Cys-containing precursors : fluorescent detection of transglycosylation and transpeptidation

Tools

Vinatier, Virginie, Blakey, Carl B., Braddick, Darren, Johnson, Benjamin R. G., Evans, Stephen D. and Bugg, Tim. (2009) In vitro biosynthesis of bacterial peptidoglycan using D-Cys-containing precursors : fluorescent detection of transglycosylation and transpeptidation. Chemical Communications (No.27). pp. 4037-4039. ISSN 1359-7345

Full text not available from this repository.

Official URL: http://dx.doi.org/10.1039/b819869a

Abstract

Peptidoglycan precursors containing D-Cys at position 4 were polymerised to form a synthetic peptidoglycan layer, which could be fluorescently labelled, providing a new method to monitor peptidoglycan transglycosylation and transpeptidation.

Item Type:

Journal Article

Subjects:

Q Science > QD Chemistry
Q Science > QP Physiology

Divisions:

Faculty of Science > Chemistry

Library of Congress Subject Headings (LCSH):

Peptidoglycans -- Synthesis, Transpeptidation, Antibacterial agents, Polymerization

Journal or Publication Title:

Chemical Communications

Publisher:

Royal Society of Chemistry

ISSN:

1359-7345

Official Date:

2009

Dates:

Date	Event
2009	Published

Number:

No.27

Number of Pages:

Page Range:

pp. 4037-4039

Identifier:

10.1039/b819869a

Status:

Peer Reviewed

Publication Status:

Published

References:

1 T. D. H. Bugg, in Comprehensive Natural Products Chemistry,
ed. M. Pinto, Elsevier, Oxford, 1999, vol. 3, pp. 241–294.
2 J. van Heijenoort, Nat. Prod. Rep., 2001, 18, 503.
3 E. Sauvage, F. Kerff, M. Terrak, J. A. Ayala and P. Charlier,
FEMS Microbiol. Rev., 2008, 32, 234.
4 A. Zapun, C. Contreras-Martel and T. Vernet, FEMS Microbiol.
Rev., 2008, 32, 361.
5 M. Terrak, T. K. Ghosh, J. van Heijenoort, J. van Beeumen,
M. Lampilas, J. Aszodi, J. A. Ayala, J.-M. Ghuysen and
M. Nguyen-Disteche, Mol. Microbiol., 1999, 34, 350.
6 X.-Y. Ye, M.-C. Lo, L. Brunner, D. Walker, D. Kahne and
S. Walker, J. Am. Chem. Soc., 2001, 123, 3155.
7 D. Barrett, C. Leimkuhler, L. Chen, D. Walker and D. Kahne
and S. Walker, J. Bacteriol., 2005, 187, 2215.
8 B. Schwartz, J. A. Markwalder, S. P. Seitz, Y. Wang and
R. L. Stein, Biochemistry, 2002, 41, 12552.
9 T.-S. A. Wang, S. A. Manning, S. Walker and D. Kahne, J. Am.
Chem. Soc., 2008, 130, 14068.
10 J. Grandchamps, M. Nguyen-Disteche, C. Damblon, J.-M. Frere
and J.-M. Ghuysen, Biochem. J., 1995, 307, 335.
11 U. Bertsche, E. Breukink, T. Kast and W. Vollmer, J. Biol. Chem.,
2005, 280, 38096.
12 J. A. Schouten, S. Bagga, A. J. Lloyd, G. De Pascale,
C. G. Dowson, D. I. Roper and T. D. H. Bugg, Mol. BioSyst.,
2006, 2, 484.
13 Y. van Heijenoort, M. Derrien and J. van Heijenoort, FEBS Lett.,
1978, 89, 141.
14 M. J. Spencelayh, Y. Cheng, R. J. Bushby, T. D. H. Bugg, J.-J. Li,
P. J. F. Henderson, J. O’Reilly and S. D. Evans, Angew. Chem., Int.
Ed., 2006, 45, 2111.
15 C. E. Dodd, B. R. G. Johnson, L. J. C. Jeuken,
T. D. H. Bugg, R. J. Bushby and S. D. Evans, Biointerphases,
2008, 3, 59.