Groom, Harriet C. T., Anderson, Emma C. and Lever, Andrew M. L. (2009) Rev: beyond nuclear export. Journal of General Virology, Vol.90 (Part 6). pp. 1303-1318. ISSN 0022-1317

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Abstract

Rev remains a hot topic. In this review, we revisit the insights that have been gained into the control of gene expression by the retroviral protein Rev and speculate on where current research is leading. We outline what is known about the role of Rev in translation and encapsidation and how these are linked to its more traditional role of nuclear export, underlining the multifaceted nature of this small viral protein. We discuss what more is to be learned in these fields and why continuing research on these 116 amino acids and understanding their function is still important in devising methods to combat AIDS.

Item Type:	Journal Item
Subjects:	T Technology > TP Chemical technology Q Science > QR Microbiology > QR355 Virology
Divisions:	Faculty of Science > Life Sciences (2010- ) > Biological Sciences ( -2010)
Journal or Publication Title:	Journal of General Virology
Publisher:	Society for General Microbiology
ISSN:	0022-1317
Date:	June 2009
Volume:	Vol.90
Number:	Part 6
Number of Pages:	16
Page Range:	pp. 1303-1318
Identification Number:	10.1099/vir.0.011460-0
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
URI:	http://wrap.warwick.ac.uk/id/eprint/27843

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