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Possible role of oxidative stress in the pathogenesis of hypertension

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Ceriello, Antonio. (2008) Possible role of oxidative stress in the pathogenesis of hypertension. Diabetes Care, Vol.31 (Suppl.2). S181-S184. ISSN 0149-5992

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Official URL: http://dx.doi.org/10.2337/dc08-s245

Abstract

Recently oxidative stress has been proposed as the cause of hypertension. An imbalance in superoxide and nitric oxide production may account for reduced vasodilation, which in turn can favor the development of hypetension. In vitro and in human studies support this hypothesis. The supplementation of antioxidants, particularly in the form of fresh fruit and vegetables, reduces blood pressure, supporting a role for free radicals in hypertension.

Item Type: Journal Article
Subjects: R Medicine > RB Pathology
R Medicine > RC Internal medicine
Divisions: Faculty of Medicine > Warwick Medical School > Clinical Sciences Research Institute (CSRI)
Library of Congress Subject Headings (LCSH): Oxidative stress, Hypertension -- Etiology
Journal or Publication Title: Diabetes Care
Publisher: American Diabetes Association
ISSN: 0149-5992
Date: February 2008
Volume: Vol.31
Number: Suppl.2
Number of Pages: 4
Page Range: S181-S184
Identification Number: 10.2337/dc08-s245
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Description: Based on a presentation at: 1st Meeting on Controversies in Obesity, Diabetes and Hypertension, Berlin, Germany, Oct, 2006
Funder: Merck Sharp & Dohme, Produits Roche S.A., Sanofi aventis (Firm), Novo Nordisk, Medtronic, Inc., Lifescan Inc., World Wide, Eli Lilly and Company, Keryx, Abbott Laboratories, Novartis (Firm), Pfizer Inc., Generx Biotechnology, Schering-Plough Corporation, Johnson & Johnson
Type of Event: Conference
URI: http://wrap.warwick.ac.uk/id/eprint/28254

Data sourced from Thomson Reuters' Web of Knowledge

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