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Exploring the regime map for high-shear mixer granulation

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Tu, Wei-Da, Ingram, Andy, Seville, J. P. K. (Jonathan P. K.) and Hsiau, Shu-San. (2009) Exploring the regime map for high-shear mixer granulation. Chemical Engineering Journal, Vol.145 (No.3). pp. 505-513. ISSN 13858947

Full text not available from this repository.
Official URL: http://dx.doi.org/10.1016/j.cej.2008.09.033

Abstract

The aim of this study was to investigate the applicability of the regime map approach proposed by Litster/Iveson and co-workers [S.M. Iveson, J.D. Litster, Growth regime map for liquid-bound granules,AlChE Journal 44 (1998) 1510-1518; S.M. Iveson, P.A.L. Wauters, S. Forrest, J.D. Litster, G.M.H. Meesters, B. Scarlett, Growth regime map for liquid-bound granules: further development and experimental validation, Powder Technology 117 (2001) 83-97] over the whole parameter range, for a given material and agglomeration method. Agglomeration behaviour in a high-shear mixer granulator was investigated and categorised using the evolution of granule size distribution (GSD). MCC 102 (Microcrystalline cellulose, Avicel 102) and aqueous PEG 6k (Polyethylene Glycol 6000) were employed as solid and liquid materials. Different operating conditions were applied by changing impeller speeds and L/S (liquid-to-solid) ratios (weight of liquid/weight of solid). 12 representative settings were selected and typical agglomeration behaviours were identified, forming a regime map for the system. The effect of impeller speed was found to depend on the L/S ratio, very little effect being seen at low L/S ratio (L/S = 85/150). but much more effect at higher binder ratios. In general, the effect of L/S ratio is of paramount importance in these systems and usually determines the growth behaviour. (c) 2008 Elsevier B.V. All rights reserved.

Item Type: Journal Article
Subjects: T Technology > TD Environmental technology. Sanitary engineering
T Technology > TP Chemical technology
Divisions: Faculty of Science > Engineering
Journal or Publication Title: Chemical Engineering Journal
Publisher: Elsevier BV
ISSN: 13858947
Date: 1 January 2009
Volume: Vol.145
Number: No.3
Number of Pages: 9
Page Range: pp. 505-513
Identification Number: 10.1016/j.cej.2008.09.033
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: National Science Council, Taiwan, R.O.C., Department of Chemical Engineering, University of Birmingham
Grant number: NSC 97-2628-E-008-036-MY3
URI: http://wrap.warwick.ac.uk/id/eprint/28771

Data sourced from Thomson Reuters' Web of Knowledge

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