Postprandial hyperglycaemia : a new risk factor for cardiovascular disease
Ceriello, Antonio (2008) Postprandial hyperglycaemia : a new risk factor for cardiovascular disease. Diabetes, Stoffwechsel und Herz, Vol.17 (No.5). pp. 363-373. ISSN 1861-7603Full text not available from this repository.
Type 2 diabetes is primarily a disorder of post-prandial glucose regulation, characterized by a gradual decline in insulin secretion in response to nutrient loads. Despite this, physicians continue to rely on fasting blood glucose and glycosylated haemoglobin (HbA(1c)) to guide management. There is a linear relationship between the risk of cardiovascular death and the 2-hour oral glucose tolerance test (OGTT). A recent study demonstrated that postprandial hyperglycaemia is an independent risk factor for cardiovascular disease in type 2 diabetes. Also, several intervention studies have shown that treating postprandial hyoerglycaemia may reduce the incidence of new cardiovascular events. Evidence supports the hypothesis that post-prandial hyperglycaemia may lead to cardiovascular disease through the generation of oxidative stress. Furthermore, clinical data suggest that post-prandial hyperglycaemia is a common phenomenon, even in patients who may be considered as having good metabolic control.
|Item Type:||Journal Item|
|Subjects:||R Medicine > RC Internal medicine|
|Divisions:||Faculty of Medicine > Warwick Medical School|
|Library of Congress Subject Headings (LCSH):||Hyperglycemia, Cardiovascular system -- Diseases -- Risk factors, Non-insulin-dependent diabetes|
|Journal or Publication Title:||Diabetes, Stoffwechsel und Herz|
|Publisher:||Verlag Kirchheim und Co. GmbH|
|Date:||20 September 2008|
|Number of Pages:||11|
|Page Range:||pp. 363-373|
|Status:||Not Peer Reviewed|
|Access rights to Published version:||Restricted or Subscription Access|
Actions (login required)