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Postprandial hyperglycaemia : a new risk factor for cardiovascular disease
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Ceriello, Antonio (2008) Postprandial hyperglycaemia : a new risk factor for cardiovascular disease. Diabetes, Stoffwechsel und Herz, Vol.17 (No.5). pp. 363-373.
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Abstract
Type 2 diabetes is primarily a disorder of post-prandial glucose regulation, characterized by a gradual decline in insulin secretion in response to nutrient loads. Despite this, physicians continue to rely on fasting blood glucose and glycosylated haemoglobin (HbA(1c)) to guide management.
There is a linear relationship between the risk of cardiovascular death and the 2-hour oral glucose tolerance test (OGTT). A recent study demonstrated that postprandial hyperglycaemia is an independent risk factor for cardiovascular disease in type 2 diabetes. Also, several intervention studies have shown that treating postprandial hyoerglycaemia may reduce the incidence of new cardiovascular events. Evidence supports the hypothesis that post-prandial hyperglycaemia may lead to cardiovascular disease through the generation of oxidative stress. Furthermore, clinical data suggest that post-prandial hyperglycaemia is a common phenomenon, even in patients who may be considered as having good metabolic control.
| Item Type: | Journal Item | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine | ||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||
| Library of Congress Subject Headings (LCSH): | Hyperglycemia, Cardiovascular system -- Diseases -- Risk factors, Non-insulin-dependent diabetes | ||||
| Journal or Publication Title: | Diabetes, Stoffwechsel und Herz | ||||
| Publisher: | Verlag Kirchheim und Co. GmbH | ||||
| ISSN: | 1861-7603 | ||||
| Official Date: | 20 September 2008 | ||||
| Dates: |
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| Volume: | Vol.17 | ||||
| Number: | No.5 | ||||
| Number of Pages: | 11 | ||||
| Page Range: | pp. 363-373 | ||||
| Status: | Not Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
Data sourced from Thomson Reuters' Web of Knowledge
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