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The cost-effectiveness of screening and treatment for hepatitis C in prisons in England and Wales : a cost-utility analysis
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Sutton, A. J., Edmunds, W. John, Sweeting, M. J. and Gill, O. N. (2008) The cost-effectiveness of screening and treatment for hepatitis C in prisons in England and Wales : a cost-utility analysis. Journal of Viral Hepatitis, Volume 15 (Number 11). pp. 797-808. doi:10.1111/j.1365-2893.2008.01008.x ISSN 1352-0504.
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Official URL: http://dx.doi.org/10.1111/j.1365-2893.2008.01008.x
Abstract
Prisoners have a high prevalence of hepatitis C virus (HCV) infection compared with the general population in England and Wales and in many locations throughout the world. This is because of large numbers of injecting drug users that engage in behaviours likely to transmit HCV being present within prison populations. It is, therefore, suggested that prison may be an appropriate location for HCV screening and treatment to be administered. Using cost-utility analysis, this study considers the costs and benefits of administering a single round of screening on reception into prison to all individuals followed by possible later screening in the community and comparing this to individuals who may only be tested and treated in the community at a later date. The cost/QALY of one round of prison testing and treatment was found to be 54,852 pound, although probabilistic sensitivity analysis showed extensive uncertainty about this estimate. One-way sensitivity analysis revealed the importance of the parameters describing the progression of chronic HCV and the discount rates. While the results presented here at baseline would suggest that screening and treatment for HCV in prisons is not cost-effective, these results are subject to much uncertainty. The importance of the rates describing the progression of chronic HCV on the cost-effectiveness of this intervention has been demonstrated and this suggests that future work should be undertaken to gain further insight into the rates that individuals progress to the later stages of chronic HCV infection.
Item Type: | Journal Article | ||||
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Subjects: | H Social Sciences > HV Social pathology. Social and public welfare R Medicine > RC Internal medicine |
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) > Biological Sciences ( -2010) | ||||
Library of Congress Subject Headings (LCSH): | Medical care -- Great Britain -- Cost effectiveness, Prisoners -- Great Britain -- Drug use, Hepatitis C, Intravenous drug abusers, Prisoners -- Diseases -- Great Britain | ||||
Journal or Publication Title: | Journal of Viral Hepatitis | ||||
Publisher: | Wiley-Blackwell Publishing Ltd. | ||||
ISSN: | 1352-0504 | ||||
Official Date: | November 2008 | ||||
Dates: |
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Volume: | Volume 15 | ||||
Number: | Number 11 | ||||
Number of Pages: | 12 | ||||
Page Range: | pp. 797-808 | ||||
DOI: | 10.1111/j.1365-2893.2008.01008.x | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Funder: | Great Britain. Department of Health (DoH) |
Data sourced from Thomson Reuters' Web of Knowledge
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