IQ and non-clinical psychotic symptoms in 12-year-olds : results from the ALSPAC birth cohort
Horwood, Jeremy, Salvi, Giovanni, Thomas, Kate, Hollis, Chris, Lewis, Glyn, Menezes, Paulo, Thompson, Andrew D., Wolke, Dieter, Zammit, Stanley and Harrison, Glynn. (2008) IQ and non-clinical psychotic symptoms in 12-year-olds : results from the ALSPAC birth cohort. British Journal of Psychiatry, 193 (3). pp. 185-191. ISSN 0007-1250Full text not available from this repository.
Official URL: http://dx.doi.org/10.1192/bjp.bp.108.051904
Background Non-clinical psychotic symptoms appear common in children, but it is possible that a proportion of reported symptoms result from misinterpretation. There is a well-established association between pre-morbid low IQ score and schizophrenia. Psychosis-like symptoms in children may also be a risk factor for psychotic disorder but their relationship with IQ is unclear.
Aims To investigate the prevalence, nature and frequency of psychosis-like symptoms in 12-year-old children and study their relationship with IQ.
Method Longitudinal study using the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort. A total of 6455 children completed screening questions for 12 psychotic symptoms followed by a semi-structured clinical assessment. IQ was assessed at 8 years of age using the Wechsler intelligence Scale for Children (3rd UK edition).
Results The 6-month period prevalence for one or more symptoms was 13.7% (95% Cl 12.8-14.5). After adjustment for confounding variables, there was a non-linear association between IQ score and psychosis-like symptoms, such that only those with below average IQ score had an increased risk of reporting such symptoms.
Conclusions Non-clinical psychotic symptoms occur in a significant proportion of 12-year-olds. Symptoms are associated with low IQ and also less strongly with a high IQ score. The pattern of association with IQ differs from that observed in schizophrenia.
|Item Type:||Journal Article|
|Subjects:||R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RJ Pediatrics
|Divisions:||Faculty of Medicine > Warwick Medical School > Mental Health and Wellbeing
Faculty of Science > Psychology
Faculty of Medicine > Warwick Medical School
|Library of Congress Subject Headings (LCSH):||Intelligence levels, Psychoses in children, Longitudinal method, Cohort analysis, Child psychopathology|
|Journal or Publication Title:||British Journal of Psychiatry|
|Publisher:||Royal College of Psychiatrists|
|Official Date:||September 2008|
|Number of Pages:||7|
|Page Range:||pp. 185-191|
|Access rights to Published version:||Restricted or Subscription Access|
|Funder:||Wellcome Trust (London, England)|
|Grant number:||072043 (WT)|
|Version or Related Resource:||Thompson, A., et al. (2008). IQ and non-clinical psychotic symptoms in 12-year olds : results from the ALSPAC birth cohort. [Abstract]. Early Intervention in Psychiatry, 2(suppl.1), pp. A55. http://wrap.warwick.ac.uk/id/eprint/27859|
1 Bijl R, Ravelli A, van Zessen G. Prevalence of psychiatric disorder in the
Actions (login required)