IQ and non-clinical psychotic symptoms in 12-year-olds : results from the ALSPAC birth cohort
Horwood, Jeremy, Salvi, Giovanni, Thomas, Kate, 1972-, Hollis, Chris, Lewis, Glyn, Menezes, Paulo, Thompson, Andrew, 1932-, Wolke, Dieter, Zammit, Stanley and Harrison, Glynn. (2008) IQ and non-clinical psychotic symptoms in 12-year-olds : results from the ALSPAC birth cohort. British Journal of Psychiatry, Vol.193 (No.3). pp. 185-191. ISSN 0007-1250Full text not available from this repository.
Official URL: http://dx.doi.org/10.1192/bjp.bp.108.051904
Background Non-clinical psychotic symptoms appear common in children, but it is possible that a proportion of reported symptoms result from misinterpretation. There is a well-established association between pre-morbid low IQ score and schizophrenia. Psychosis-like symptoms in children may also be a risk factor for psychotic disorder but their relationship with IQ is unclear.
Aims To investigate the prevalence, nature and frequency of psychosis-like symptoms in 12-year-old children and study their relationship with IQ.
Method Longitudinal study using the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort. A total of 6455 children completed screening questions for 12 psychotic symptoms followed by a semi-structured clinical assessment. IQ was assessed at 8 years of age using the Wechsler intelligence Scale for Children (3rd UK edition).
Results The 6-month period prevalence for one or more symptoms was 13.7% (95% Cl 12.8-14.5). After adjustment for confounding variables, there was a non-linear association between IQ score and psychosis-like symptoms, such that only those with below average IQ score had an increased risk of reporting such symptoms.
Conclusions Non-clinical psychotic symptoms occur in a significant proportion of 12-year-olds. Symptoms are associated with low IQ and also less strongly with a high IQ score. The pattern of association with IQ differs from that observed in schizophrenia.
|Item Type:||Journal Article|
|Subjects:||R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RJ Pediatrics
|Divisions:||Faculty of Science > Psychology|
|Library of Congress Subject Headings (LCSH):||Intelligence levels, Psychoses in children, Longitudinal method, Cohort analysis, Child psychopathology|
|Journal or Publication Title:||British Journal of Psychiatry|
|Publisher:||Royal College of Psychiatrists|
|Official Date:||September 2008|
|Number of Pages:||7|
|Page Range:||pp. 185-191|
|Access rights to Published version:||Restricted or Subscription Access|
|Funder:||Wellcome Trust (London, England)|
|Grant number:||072043 (WT)|
|Version or Related Resource:||Thompson, A., et al. (2008). IQ and non-clinical psychotic symptoms in 12-year olds : results from the ALSPAC birth cohort. [Abstract]. Early Intervention in Psychiatry, 2(suppl.1), pp. A55. http://wrap.warwick.ac.uk/id/eprint/27859|
1 Bijl R, Ravelli A, van Zessen G. Prevalence of psychiatric disorder in the
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