Horwood, Jeremy, Salvi, Giovanni, Thomas, Kate, 1972-, Hollis, Chris, Lewis, Glyn, Menezes, Paulo, Thompson, Andrew, 1932-, Wolke, Dieter, Zammit, Stanley and Harrison, Glynn. (2008) IQ and non-clinical psychotic symptoms in 12-year-olds : results from the ALSPAC birth cohort. British Journal of Psychiatry, Vol.193 (No.3). pp. 185-191. ISSN 0007-1250

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Abstract

Background Non-clinical psychotic symptoms appear common in children, but it is possible that a proportion of reported symptoms result from misinterpretation. There is a well-established association between pre-morbid low IQ score and schizophrenia. Psychosis-like symptoms in children may also be a risk factor for psychotic disorder but their relationship with IQ is unclear. Aims To investigate the prevalence, nature and frequency of psychosis-like symptoms in 12-year-old children and study their relationship with IQ. Method Longitudinal study using the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort. A total of 6455 children completed screening questions for 12 psychotic symptoms followed by a semi-structured clinical assessment. IQ was assessed at 8 years of age using the Wechsler intelligence Scale for Children (3rd UK edition). Results The 6-month period prevalence for one or more symptoms was 13.7% (95% Cl 12.8-14.5). After adjustment for confounding variables, there was a non-linear association between IQ score and psychosis-like symptoms, such that only those with below average IQ score had an increased risk of reporting such symptoms. Conclusions Non-clinical psychotic symptoms occur in a significant proportion of 12-year-olds. Symptoms are associated with low IQ and also less strongly with a high IQ score. The pattern of association with IQ differs from that observed in schizophrenia.

Item Type:	Journal Article
Subjects:	R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry R Medicine > RJ Pediatrics
Divisions:	Faculty of Science > Psychology
Library of Congress Subject Headings (LCSH):	Intelligence levels, Psychoses in children, Longitudinal method, Cohort analysis, Child psychopathology
Journal or Publication Title:	British Journal of Psychiatry
Publisher:	Royal College of Psychiatrists
ISSN:	0007-1250
Date:	September 2008
Volume:	Vol.193
Number:	No.3
Number of Pages:	7
Page Range:	pp. 185-191
Identification Number:	10.1192/bjp.bp.108.051904
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Wellcome Trust (London, England)
Grant number:	072043 (WT)
Version or Related Resource:	Thompson, A., et al. (2008). IQ and non-clinical psychotic symptoms in 12-year olds : results from the ALSPAC birth cohort. [Abstract]. Early Intervention in Psychiatry, 2(suppl.1), pp. A55. http://wrap.warwick.ac.uk/id/eprint/27859
Related URLs:	Related item in WRAP
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URI:	http://wrap.warwick.ac.uk/id/eprint/29311

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