The Library

Two Leishmania species circulating in the Kaleybar focus of infantile visceral leishmaniasis, northwest Iran: implications for deltamethrin dog collar intervention

Tools

Parvizi, P., Mazloumi-Gavgani, A. S., Davies, C. R., Courtenay, Orin and Ready, P. D. (Paul Donald). (2008) Two Leishmania species circulating in the Kaleybar focus of infantile visceral leishmaniasis, northwest Iran: implications for deltamethrin dog collar intervention. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol.102 (No.9). pp. 891-897. ISSN 0035-9203

Full text not available from this repository.

Official URL: http://dx.doi.org/10.1016/j.trstmh.2008.04.026

Abstract

Leishmania infantum is the causative agent of infantile visceral leishmaniasis (IVL) in the Mediterranean Basin and, based on isoenzyme typing of a few isolates from patients and domestic dogs, this parasite was considered to predominate in the Kaleybar focus of IVL in northwest Iran. However, in the current investigation only one out of five sandfly infections was found to be L. infantum, based on PCR detection and sequencing of parasite internal transcribed spacer (ITS) rDNA infecting Phlebotomus perfiliewi transcaucasicus. The four other infections were of haplotypes of L. tropica, the causative agent of anthroponotic cutaneous leishmaniasis in the Middle East and a parasite occasionally detected in the viscera of dogs and patients in Iran and elsewhere. The widespread distribution of L. tropica in the Kaleybar focus suggests that this parasite is not a transient introduction. Kaleybar has been used for a deltamethrin dog collar intervention to reduce the biting rates of the vectors of L. infantum and this has significantly reduced the incidence of Leishmania infections both in children and the domestic dog, the usual reservoir host of IVL. The implications of finding L. tropica widespread in the heart of the intervention area are discussed. Extensive and intensive typing of natural Leishmania infections is a characteristic of epidemiological investigations in the Neotropics and the current report indicates that this will also be necessary in some regions of the Old World. (C) 2008 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

Item Type:

Journal Article

Subjects:

Q Science > QL Zoology
R Medicine > RC Internal medicine

Divisions:

Faculty of Science > Life Sciences (2010- )

Library of Congress Subject Headings (LCSH):

Kala-azar -- Prevention -- Iran, Leishmaniasis -- Prevention -- Iran, Leishmania, Leishmaniasis -- Iran, Polymerase chain reaction -- Diagnostic use, Dog collars

Journal or Publication Title:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Publisher:

Elsevier Ltd

ISSN:

0035-9203

Official Date:

September 2008

Dates:

Date	Event
September 2008	Published

Volume:

Vol.102

Number:

No.9

Number of Pages:

Page Range:

pp. 891-897

Identifier:

10.1016/j.trstmh.2008.04.026

Status:

Peer Reviewed

Publication Status:

Published

Access rights to Published version:

Restricted or Subscription Access

Funder:

Wellcome Trust (London, England)

Grant number:

076266 (WT)

References:

Alborzi, A., Rasouli, M., Shamsizadeh, A., 2006. Leishmania
tropica—–isolated patient with visceral leishmaniasis in southern
Iran. Am. J. Trop. Med. Hyg. 74, 306—307.
Berenji, F., Yaghoobi-Ershadi, M.R., Akhavan, A.A., Hanafi-Bojd,
A.A., Fata, A., 2006. A study on the vectors of the cutaneous
leishmaniasis in the northern part of Mashad, Iran. Arch. Iran.
Med. 9, 1—6.
Crum, N.F., Aronson, N.E., Lederman, E.R., Rusnak, J.M., Cross,
J.H., 2005. History of U.S. military contributions to the study of
parasitic diseases. Mil. Med. 170 (Suppl. 1), 17—29.
Davies, C.R., Mazloumi-Gavgani, A.S., 1999. Age, acquired immunity
and the risk of visceral leishmaniasis: a prospective study in
Iran. Parasitology 119, 247—257.
Desjeux, P., 2001. The increase in risk factors for leishmaniasis
worldwide. Trans. R. Soc. Trop. Med. Hyg. 95, 239—243.
Dye, C., Guy, M.W., Elkins, D.B., Wilkes, T.J., Killick-Kendrick, R.,
1987. The life expectancy of phlebotomine sandflies: first field
estimates from southern France. Med. Vet. Entomol. 1, 417—425.
Gallego, M., Pratlong, F., Fisa, R., Riera, C., Rioux, J.A., Dedet,
J.P., Portus, M., 2001. The life-cycle of Leishmania infantum
MON-77 in the Priorat (Catalonia, Spain) involves humans, dogs
and sandflies: also literature review of distribution and hosts of
L. infantum zymodemes in the Old World. Trans. R. Soc. Trop.
Med. Hyg. 95, 269—271.
Gavgani, A.S.M., 1998. Diagnosis and epidemiological studies of
visceral leishmaniasis in north-west Iran. PhD thesis, London
University, UK.
Gavgani, A.S.M., Hodjati, M.H., Mohite, H., Davies, C.R., 2002a.
Effect of insecticide-impregnated dog collars on incidence rate
of zoonotic visceral leishmaniasis in children: a matched-cluster
randomised trial. Lancet 360, 374—379.
Gavgani, A.S.M., Mohite, H., Edrissian, G.H., Mohebali, M., Davies,
C.R., 2002b. Domestic dog ownership in Iran is a risk factor for
human infection with Leishmania infantum. Am. J. Trop. Med.
Hyg. 67, 511—515.
Hajjaran, H., Mohebali, M., Zarei, Z., Edrissian, G.H., 2007. Leishmania
tropica: another etiological agent of canine visceral
leishmaniasis in Iran. Iran. J. Public Health 36, 85—88.
Killick-Kendrick, R., 1990. Phlebotomine vectors of the leishmaniases:
a review. Med. Vet. Entomol. 4, 1—24.
Killick-Kendrick, R., Ward, R.D., 1981. Ecology of Leishmania. Parasitology
82, 143—152.
Lainson, R., Shaw, J.J., Silveira, F.T., 1987. Dermal and visceral
leishmaniasis and their causative agents. Trans. R. Soc. Trop.
Med. Hyg. 81, 702—703.
Lewis, D.J., 1982. A taxonomic review of the genus Phlebotomus
(Diptera: Psychodidae). Bull. Br. Mus. (Nat. Hist., Ent.) 45,
121—209.
Lukes, J., Mauricio, I.L., Shonian, G., Dujardin, J.-C., Soteriadou,
K., Dedet, J.P., Kuhls, K., Tintaya, K.W.Q., Jirku, M.,
Chocholova, E., Haralambous, C., Pratlong, F., Obornik, M.,
Horak, A., Ayala, F.J., Miles, M.A., 2007. Evolutionary and geographical
history of the Leishmania donovani complex with a
revision of current taxonomy. Proc. Natl. Acad. Sci. USA 104,
9375—9380.
Magill, A.J., Gr¨ogl, M., Gasser Jr., R.A., Sun, W., Oster, C.N., 1993.
Visceral infection caused by Leishmania tropica in veterans of
Operation Desert Storm. N. Engl. J. Med. 328, 1383—1387.
Magill, A.J., Gr¨ogl, M., Johnson, S.C., Gasser Jr., R.A., 1994.
Visceral infection due to Leishmania tropica in a veteran of
Operation Desert Storm who presented 2 years after leaving
Saudi Arabia. Clin. Infect. Dis. 19, 805—806.
Mohebali, M., Yaghoobi-Ershadi, M.R., Akhavan, A.A., Hajjaran, H.,
Abaei, M.R., 2004. Characterization of Leishmania infection in
rodents from endemic areas of the Islamic Republic of Iran. East
Mediterr. Health J. 10, 591—599.
Mohebali, M., Hajjaran, H., Hamzavi, Y., Mobedi, I., Arshi, S.H.,
Zarei, Z., Akhoundi, B., Naeini, M.K., Avizeh, R., Fakhar,
M., 2005. Epidemiological aspects of canine visceral leishmaniosis
in the Islamic Republic of Iran. Vet. Parasitol. 129,
243—251.
Motazedian, H., Noamanpoor, B., Ardehali, S., 2002. DNA extraction
and amplification of Leishmania from archived, Giemsa-stained
slides, for the diagnosis of cutaneous leishmaniasis by PCR. Ann.
Trop. Med. Parasitol. 96, 31—34.
Nadim, A., Javadian, E., 1976. Key for species identification of sandflies
(Phlebotominae; Diptera) of Iran. Iran. J. Public Health 5,
35—44.
Nadim, A., Seyedi-Rashti, M.A., 1971. A brief review of the epidemiology
of various types of leishmaniasis in Iran. Acta Med. Iran.
14, 99—106.
Nadim, A., Navid-Hamidi, A., Javadian, E., Tahvildari Bidruni, G.H.,
Amini, H., 1978. Present status of kala-azar in Iran. Am. J. Trop.
Med. Hyg. 27, 25—28.
Nadim, A., Javadian, E., Tahvildari Bidruni, G.H., Mottaghi, M.,
Abai, M.R., 1992. Epidemiological aspects of kala-azar in
Meshkin-Shahr, Iran: investigation on vectors. Iran. J. Public
Health 21, 61—72.
Parvizi, P., Ready, P.D., 2007. Three Leishmania infections of Gerbillidae
group in sandflies from two known ZCL foci of Iran by
using molecular techniques. Iran. J. Infect. Dis. Trop. Med. 12,
11—22.
Parvizi, P., Mauricio, I., Aransay, A.M., Miles, M.A., Ready, P.D.,
2005. First detection of Leishmania major in peridomestic
Iranian sandflies: comparison of nested PCR of nuclear ITS ribo
Acta Trop. 93, 75—83.
Rassi, Y., Javadian, E., Nadim, A., Zahraii, A., Vatandoost, H.,
Motazedian, H., Azizi, K., Mohebali, M., 2005. Phlebotomus
(Larroussius) kandelakii, the principal and proven vector of visceral
leishmaniasis in North West of Iran. Pak. J. Biol. Sci. 8,
1802—1806.
Sudia, W.D., Chamberland, R.W., 1962. Battery-operated light trap,
an improved model. Mosq. News 22, 126—129.
Swofford, D.L., 2002. PAUP*: Phylogenetic Analysis Using Parsimony
(* and other methods) version 4.0. Sinauer Associates, Inc., Sunderland,
MA.