Mann, Nicholas H.. (2008) The potential of phages to prevent MRSA infections. Research in Microbiology, Vol.159 (No.5). pp. 400-405. ISSN 0923-2508

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Abstract

This short review attempts to examine whether there is a potential for the use of phages capable of infecting Staphylococcus aureus to eradicate or reduce nasal colonisation, thereby reducing the overall infection burden in patient populations identified as being at risk from MRSA infections. There is clear evidence that nasal decolonisation may be of benefit to certain patient groups and also that phages can effectively combat experimentally induced S. aureus infections in animals. However, this is not in itself enough to validate the use of phages for decolonisation and, given the appearance of strains resistant to currently used topical antibiotics, there is a need for clinical trials of this prophylactic use of phages. (C) 2008 Elsevier Masson SAS. All rights reserved.

Item Type:	Journal Article
Subjects:	Q Science > QR Microbiology R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions:	Faculty of Science > Life Sciences (2010- )
Library of Congress Subject Headings (LCSH):	Staphylococcus aureus infections, Nosocomial infections, Biofilms, Bacteriophages -- Research
Journal or Publication Title:	Research in Microbiology
Publisher:	Elsevier Science BV
ISSN:	0923-2508
Date:	June 2008
Volume:	Vol.159
Number:	No.5
Number of Pages:	6
Page Range:	pp. 400-405
Identification Number:	10.1016/j.resmic.2008.04.003
Status:	Peer Reviewed
Publication Status:	Published
URI:	http://wrap.warwick.ac.uk/id/eprint/29320

Data sourced from Thomson Reuters' Web of Knowledge

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