
The Library
Petrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N-8-citryl-spermidine and its N-1-(3,4-dihydroxybenzoyl) derivative
Tools
Oves-Costales, Daniel, Kadi, Nadia, Fogg, Mark J., Song, Lijiang, Wilson, Keith S. and Challis, Gregory L. (2008) Petrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N-8-citryl-spermidine and its N-1-(3,4-dihydroxybenzoyl) derivative. Chemical Communications (No.34). pp. 4034-4036. doi:10.1039/b809353a ISSN 1359-7345.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1039/b809353a
Abstract
The AsbB enzyme, which is involved in the biosynthesis of the virulence-conferring siderophore petrobactin in Bacillus anthracis, is shown to catalyze efficient ATP-dependent condensation of spermidine, but not N-1-(3,4-dihydroxbenzoyl)-spermidine, with N-8-citryl-spermidine or N-1-(3,4-dihydroxbenzoyl)-N-8-citryl-spermidine, suggesting that N-1-(3,4-dihydroxbenzoyl)-spermidine is very unlikely to be a significant intermediate in petrobactin biosynthesis, contrary to previous suggestions.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Library of Congress Subject Headings (LCSH): | Siderophores -- Synthesis, Siderophores -- Therapeutic use, Spermidine | ||||
Journal or Publication Title: | Chemical Communications | ||||
Publisher: | Royal Society of Chemistry | ||||
ISSN: | 1359-7345 | ||||
Official Date: | 14 September 2008 | ||||
Dates: |
|
||||
Number: | No.34 | ||||
Number of Pages: | 3 | ||||
Page Range: | pp. 4034-4036 | ||||
DOI: | 10.1039/b809353a | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Funder: | Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC) | ||||
Grant number: | BB/FO13760/1 (BBSRC) |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Repository staff actions (login required)
![]() |
View Item |