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Cybrid human embryos - warranting opportunities to augment embryonic stem cell research
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Fulka, Josef, Fulka, Helena, St. John, Justin C., Galli, C. (Cesare), Lazzari, Giovanna, Lagutina, Irina and Loi, Pasqualino (2008) Cybrid human embryos - warranting opportunities to augment embryonic stem cell research. Trends in Biotechnology, Vol.26 (No.9). pp. 469-474. doi:10.1016/j.tibtech.2008.06.001
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Official URL: http://dx.doi.org/10.1016/j.tibtech.2008.06.001
Abstract
The recent vote in the British Parliament allows scientists in principle to create hybrid embryos by transferring human somatic cell nuclei into animal oocytes. This vote opens a fascinating new area of research with the central aim of generating interspecific lines of embryonic stem cells (ESCs) that could potentially be used to understand development, differentiation, gene expression and genomic compatibility. It will also promote human cell therapies, as well as the pharmaceutical industry's search for new drug targets. If this approach is to be successful, many biological questions need to be answered and, in addition, some moral and ethical aspects must be taken into account.
| Item Type: | Journal Item | ||||
|---|---|---|---|---|---|
| Subjects: | Q Science > QH Natural history > QH301 Biology | ||||
| Divisions: | Faculty of Medicine > Warwick Medical School | ||||
| Library of Congress Subject Headings (LCSH): | Embryonic stem cells -- Research, Ovum, Embryology | ||||
| Journal or Publication Title: | Trends in Biotechnology | ||||
| Publisher: | Elsevier Science BV | ||||
| ISSN: | 0167-7799 | ||||
| Official Date: | September 2008 | ||||
| Dates: |
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| Volume: | Vol.26 | ||||
| Number: | No.9 | ||||
| Number of Pages: | 6 | ||||
| Page Range: | pp. 469-474 | ||||
| DOI: | 10.1016/j.tibtech.2008.06.001 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Funder: | European Science Foundation (ESF), Medical Research Council (Great Britain) (MRC), British Heart Foundation | ||||
| Grant number: | STE/05/E004 (ESF), ERAS-CT02003–980409 (ESF) |
Data sourced from Thomson Reuters' Web of Knowledge
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