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Cybrid human embryos - warranting opportunities to augment embryonic stem cell research

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Fulka, Josef, Fulka, Helena, St. John, Justin C., Galli, C. (Cesare), Lazzari, Giovanna, Lagutina, Irina and Loi, Pasqualino (2008) Cybrid human embryos - warranting opportunities to augment embryonic stem cell research. Trends in Biotechnology, Vol.26 (No.9). pp. 469-474. doi:10.1016/j.tibtech.2008.06.001

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Official URL: http://dx.doi.org/10.1016/j.tibtech.2008.06.001

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Abstract

The recent vote in the British Parliament allows scientists in principle to create hybrid embryos by transferring human somatic cell nuclei into animal oocytes. This vote opens a fascinating new area of research with the central aim of generating interspecific lines of embryonic stem cells (ESCs) that could potentially be used to understand development, differentiation, gene expression and genomic compatibility. It will also promote human cell therapies, as well as the pharmaceutical industry's search for new drug targets. If this approach is to be successful, many biological questions need to be answered and, in addition, some moral and ethical aspects must be taken into account.

Item Type: Journal Item
Subjects: Q Science > QH Natural history > QH301 Biology
Divisions: Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Embryonic stem cells -- Research, Ovum, Embryology
Journal or Publication Title: Trends in Biotechnology
Publisher: Elsevier Science BV
ISSN: 0167-7799
Official Date: September 2008
Dates:
DateEvent
September 2008Published
Volume: Vol.26
Number: No.9
Number of Pages: 6
Page Range: pp. 469-474
DOI: 10.1016/j.tibtech.2008.06.001
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: European Science Foundation (ESF), Medical Research Council (Great Britain) (MRC), British Heart Foundation
Grant number: STE/05/E004 (ESF), ERAS-CT02003–980409 (ESF)

Data sourced from Thomson Reuters' Web of Knowledge

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