Copas, John B. and Malley, Paul F. (2008) A robust P-value for treatment effect in meta-analysis with publication bias. Statistics in Medicine, Vol.27 (No.21). pp. 4267-4278. doi:10.1002/sim.3284

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Abstract

Publication bias is a major and intractable problem in meta-analysis. There have been several attempts in the literature to adapt methods to allow for such bias, but these are only possible if we are prepared to make strong assumptions about the underlying selection mechanism. We discuss the assumption that the probability that a paper is published may depend in some unspecified way on the P-value being claimed by that Study. We suggest a new robust P-value for the overall treatment effect, which turns Out to be closely related to the correlation of the associated radial plot. Properties of the method arc discussed Bind illustrated in two examples. Copyright (c) 2008 John Wiley & Sons, Ltd.

Item Type:	Journal Article
Subjects:	Q Science > QA Mathematics R Medicine > R Medicine (General)
Divisions:	Faculty of Science > Statistics
Library of Congress Subject Headings (LCSH):	Meta-analysis, Medicine -- Research -- Evaluation, Sensitivity theory (Mathematics), Statistical hypothesis testing
Journal or Publication Title:	Statistics in Medicine
Publisher:	John Wiley & Sons Ltd.
ISSN:	0277-6715
Official Date:	20 September 2008
Dates:	Date Event 20 September 2008 Published
Volume:	Vol.27
Number:	No.21
Number of Pages:	12
Page Range:	pp. 4267-4278
DOI:	10.1002/sim.3284
Status:	Peer Reviewed
Publication Status:	Published
Funder:	Engineering and Physical Sciences Research Council (EPSRC)
Grant number:	GR/S67807/01 (EPSRC)

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