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Photochemotherapy : targeted activation of metal anticancer complexes
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Farrer, Nicola J. and Sadler, P. J.. (2008) Photochemotherapy : targeted activation of metal anticancer complexes. Australian Journal of Chemistry, Vol.61 (No.9). pp. 669-674. ISSN 0004-9425
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Official URL: http://dx.doi.org/10.1071/CH08088
Abstract
The present article highlights recent findings in the field of photoactivation of anticancer metal complexes. Developments of some photoactivatable Rh-, Pt-, and Fe- based complexes are discussed and their mechanisms of anticancer action are outlined. Features required for the successful design of photoactive drugs are considered, in particular methods for improving the targeting and selectivity of such complexes through techniques such as conjugate delivery and multiphoton absorption.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | Faculty of Science > Chemistry |
| Library of Congress Subject Headings (LCSH): | Cancer -- Photochemotherapy, Antineoplastic agents -- Research, Metal complexes |
| Journal or Publication Title: | Australian Journal of Chemistry |
| Publisher: | CSIRO Publishing |
| ISSN: | 0004-9425 |
| Date: | 2008 |
| Volume: | Vol.61 |
| Number: | No.9 |
| Number of Pages: | 6 |
| Page Range: | pp. 669-674 |
| Identification Number: | 10.1071/CH08088 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| URI: | http://wrap.warwick.ac.uk/id/eprint/29429 |
Data sourced from Thomson Reuters' Web of Knowledge
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