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Health-related quality of life for extremely low birth weight adolescents in Canada, Germany, and the Netherlands

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Verrips, Erik, Vogels, Ton, Saigal, Saroj, Wolke, Dieter, Meyer, R. (Renate), Hoult, Lorraine and Verloove-Vanhorick, Pauline (2008) Health-related quality of life for extremely low birth weight adolescents in Canada, Germany, and the Netherlands. Pediatrics, Vol.122 (No.3). pp. 556-561. doi:10.1542/peds.2007-1043

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Official URL: http://dx.doi.org/10.1542/peds.2007-1043

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Abstract

OBJECTIVE. The goal was to compare health-related quality of life of 12- to 16-year-old adolescents born at an extremely low birth weight in regional cohorts from Ontario (Canada), Bavaria (Germany), and the Netherlands.

METHODS. Patients were extremely low birth weight survivors from Canada, Germany, and the Netherlands. Health-related quality of life was assessed with Health Utilities Index 3. Missing data were substituted by proxy reports. Differences in mean Health Utilities Index 3 scores were tested by using analysis of variance. Differences in the numbers of children with affected attributes were tested by using logistic regression analyses.

RESULTS. Survival rates were similar; response rates varied between 71% and 90%. Significant differences in health-related quality of life were found between the cohorts, with Dutch children scoring highest on Health Utilities Index 3 and German children scoring lowest, independent of birth weight, gestational age, and cerebral palsy. Differences in mean utility scores were mainly attributable to differences in the cognition health attribute. Most of the results were corroborated by logistic regression analyses.

CONCLUSIONS. There were significant differences between the 3 cohorts in health-related quality of life, not related to differences in birth weight, gestational age, or cerebral palsy. Survival and response rates alone cannot explain these differences.

Item Type: Journal Article
Subjects: R Medicine > RA Public aspects of medicine
R Medicine > RJ Pediatrics
Divisions: Faculty of Science > Psychology
Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Quality of life -- Cross-cultural studies, Health status indicators, Birth weight, Low, Teenagers -- Health and hygiene -- Research
Journal or Publication Title: Pediatrics
Publisher: American Academy of Pediatrics
ISSN: 0031-4005
Official Date: 2008
Dates:
DateEvent
2008Published
Volume: Vol.122
Number: No.3
Number of Pages: 6
Page Range: pp. 556-561
DOI: 10.1542/peds.2007-1043
Status: Peer Reviewed
Publication Status: Published
Funder: United States. Agency for Health Care Policy and Research (AHCPR), Germany. Bundesministerium für Bildung und Forschung [Germany. Federal Ministry of Education and Research] (BMBF), Germany. Bundesministerium für Bildung und Wissenschaft [Germany. German Ministry of Education and Science] (BMBW), Deutsche Forschungsgemeinschaft (DFG)
Grant number: HS-08385 (AHCPR), FKZ 01 EP 9504 (BMBW), FKZ SCHN 315/151 (DFG), JUG 14 (BMBF)

Data sourced from Thomson Reuters' Web of Knowledge

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