Pattaranit, Ratchada and Berg, Hugo van den, 1968- (2008) Mathematical models of energy homeostasis. Journal of The Royal Society Interface, Vol.5 (No.27). pp. 1119-1135. ISSN 1742-5689

Full text not available from this repository.

Abstract

Diabetes and obesity present a mounting global challenge. Clinicians are increasingly turning to mechanism-based mathematical models for a quantitative definition of physiological defects such as insulin resistance, glucose intolerance and elevated obesity set points, and for predictions of the likely outcomes of therapeutic interventions. However, a very large range of such models is available, making a judicious choice difficult. To better inform this choice, here we present the most important models published to date in a uniform format, discussing similarities and differences in terms of the decisions faced by modellers. We review models for glucostasis, based on the glucose insulin feedback control loop, and consider extensions to long-term energy balance, dislipidaemia and obesity.

Item Type:	Journal Item
Subjects:	Q Science
Divisions:	Faculty of Science > Mathematics Faculty of Science > Molecular Organisation and Assembly in Cells (MOAC)
Journal or Publication Title:	Journal of The Royal Society Interface
Publisher:	The Royal Society Publishing
ISSN:	1742-5689
Date:	6 October 2008
Volume:	Vol.5
Number:	No.27
Number of Pages:	17
Page Range:	pp. 1119-1135
Identification Number:	10.1098/rsif.2008.0216
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Thai government, MOAC Doctoral Training Centre at Warwick University
URI:	http://wrap.warwick.ac.uk/id/eprint/29507

Data sourced from Thomson Reuters' Web of Knowledge

Request changes to a record

Actions (login required)

View Item