How strong is the association between abdominal obesity and the incidence of type 2 diabetes?
Freemantle, Nick, Holmes, J. (Jeremy), Hockey, A. and Kumar, Sudhesh. (2008) How strong is the association between abdominal obesity and the incidence of type 2 diabetes? International Journal of Clinical Practice, Volume 62 (Number 9). pp. 1391-1396. ISSN 1368-5031
WRAP_Kumar_j.1742-1241.2008.01805.x - Published Version
Available under License Creative Commons Attribution Non-commercial.
Official URL: http://dx.doi.org/10.1111/j.1742-1241.2008.01805.x
Background: Quantitative evidence on the strength of the association between abdominal obesity and the incidence of type 2 diabetes was assessed. Methods: Systematic review of longitudinal studies assessing the relationship between measures reflecting abdominal obesity and the incidence of type 2 diabetes. Results: There was a strong association between measures reflecting abdominal obesity and the incidence of type 2 diabetes, the pooled odds ratio was 2.14 (95% CI: 1.70-2.71; p < 0.0001). Waist circumference (WC) was at least as good as other measures in predicting outcome. Conclusions: There is a strong association between measures reflecting abdominal obesity and the development of type 2 diabetes. Reducing WC may reduce the risk of developing type 2 diabetes.
|Item Type:||Journal Article|
R Medicine > RC Internal medicine
|Divisions:||Faculty of Science > Life Sciences (2010- ) > Biological Sciences ( -2010)
Faculty of Medicine > Warwick Medical School
|Library of Congress Subject Headings (LCSH):||Diabetes , Obesity, Meta-analysis, Systematic reviews (Medical research)|
|Journal or Publication Title:||International Journal of Clinical Practice|
|Publisher:||Wiley-Blackwell Publishing, Inc|
|Number of Pages:||6|
|Page Range:||pp. 1391-1396|
|Access rights to Published version:||Open Access|
|Funder:||Sanofi Aventis (Firm)|
|References:||1 Kissebah AH, Krakower GR. Regional adiposity and morbidity. Physiol Rev 1994; 74: 761–809. 2 Schmidt MI, Duncan BB, Canani LH, Karohl C, Chambless L. Association of waist–hip ratio with diabetes mellitus. Strength and possible modifiers. Diabetes Care 1992; 15: 912–4. 3 Cassano PA, Rosner B, Vokonas PS, Weiss ST. Obesity and body fat distribution in relation to the incidence of non-insulindependent diabetes mellitus. A prospective cohort study of men in the normative aging study. Am J Epidemiol 1992; 136: 1474–86. 4 Snijder MB, Dekker JM, Visser M et al. Associations of hip and thigh circumferences independent of waist circumference with the incidence of type 2 diabetes: the Hoorn Study. Am J Clin Nutr 2003; 77: 1192–7. 5 Wang Y, Rimm EB, Stampfer MJ, Willett WC, Hu FB. Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am J Clin Nutr 2005; 81: 555–63. 6 Wei M, Gaskill SP, Haffner SM, Stern MP. Waist circumference as the best predictor of noninsulin dependent diabetes (NIDDM) compared to body mass index, waist ⁄ hip ratio and other anthropometric measurements in Mexican Americans – a 7-year prospective study. Obes Res 1997; 5: 16–23. 7 McNeely MJ, Boyko EJ, Shofer JB, Newell-Morris L, Leonetti DL, Fujimoto WY. Standard definitions of overweight and central adiposity for determining diabetes risk in Japanese Americans. Am J Clin Nutr 2001; 74: 101–7. 8 Wang SL, Pan WH, Hwu CM et al. Incidence of NIDDM and the effects of gender, obesity and hyperinsulinaemia in Taiwan. Diabetologia 1997; 40: 1431–8. 9 Kaye SA, Folsom AR, Sprafka JM, Prineas RJ, Wallace RB. Increased incidence of diabetes mellitus in relation to abdominal adiposity in older women. J Clin Epidemiol 1991; 44: 329–34. 10 Carey V J, Walters EE, Colditz GA et al. Body fat distribution and risk of non-insulin-dependent diabetes mellitus in women. The Nurses’ Health Study. Am J Epidemiol 1997; 145: 614–9. 11 Chihaoui M, Kanoun F, Ben Rehaiem B et al. Predictive risk factors for deterioration from normoglycemic state to type 2 diabetes mellitus or impaired glucose tolerance in a Tunisian urban population. Diabetes Metab 2001; 27: 487–95. 12 Boyko EJ, Fujimoto WY, Leonetti DL, Newell-Morris L. Visceral adiposity and risk of type 2 diabetes: a prospective study among Japanese Americans. Diabetes Care 2000; 23: 465–71. 13 Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997; 20: 1183– 97. 14 Vazquez G, Duval S, Jacobs DR, Silventoinen K. Comparison of body mass index, waist circumference, and waist ⁄ hip ratio in predicting incident diabetes: a meta analysis. Epidemiol Rev 2007; 29: 115–28. 15 Koning L, Nerchant AT, Pogue J, Anand S. Waist circumference and waist-to-hip ration as predictors of cardiovascular events: meta-regression analysis of prospective studies. Eur Heart J 2007; 28: 850–6. 16 Tuomilehto J, Lindstrom J, Eriksson JG et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001; 344: 1343–50. 17 Knowler WC, Barrett-Connor E, Fowler SE et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346: 393–403. 18 Meisinger C, Do¨ring A, Thorand B, Heier M, Lo¨wel H. Body fat distribution and risk of type 2 diabetes in the general population: are there difference between men and women? The MONICA ⁄ KORA Augsburg Cohort Study. Am J Clin Nutr 2006; 84: 483–9.|
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