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The potential impact of periodontal disease on general health : a consensus view
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Williams, Ray C., Barnett, A. H., Claffey, Noel, Davis, M., Gadsby, Roger, Kellett, Margaret, Lip, Gregory Y. H. and Thackray, S. (2008) The potential impact of periodontal disease on general health : a consensus view. Current Medical Research and Opinion, Vol.24 (No.6). pp. 1635-1643. doi:10.1185/03007990802131215
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Official URL: http://dx.doi.org/10.1185/03007990802131215
Abstract
Background: Evidence for a link between periodontal disease and several systemic diseases is growing rapidly. The infectious and inflammatory burden of chronic periodontitis is thought to have an important systemic impact. Current evidence suggests that periodontitis is associated with an increased likelihood of coronary heart disease and may influence the severity of diabetes.
Scope: This paper represents a UK and Ireland cross-specialty consensus review, undertaken by a group of physicians and dentists. The consensus group reviewed published evidence (PubMed search for review and original articles), focusing on the past 5 years, on the contributory role of periodontal disease to overall health. In particular, evidence relating to a role for periodontal disease in cardiovascular disease and in diabetes was considered.
Findings: Initial studies of large epidemiological data sets have sought to find links between periodontitis and systemic disease outcomes, but a causal relationship still needs to be demonstrated between periodontal disease, cardiovascular disease and diabetes through prospective studies. There is a need for prospective studies assessing the association between periodontal disease and patients at particular risk of cardiovascular events which will allow assessment of both cardiovascular disease clinical endpoints and surrogate markers of cardiovascular risk. Of note, periodontal disease is also often more severe in subjects with diabetes mellitus, a group at already increased risk for cardiovascular events.
Conclusions: While further research is needed to define the population-attributable risk of periodontal disease to both cardiovascular diseases and to diabetes control and progression, health education to encourage better oral health should be considered as part of current healthy lifestyle messages designed to reduce the increasing health burden of obesity, cardiovascular disease and diabetes.
| Item Type: | Journal Item | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine R Medicine > RK Dentistry |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||
| Library of Congress Subject Headings (LCSH): | Periodontal disease, Cardiovascular system -- Diseases, Mouth -- Care and hygiene, Diabetes | ||||
| Journal or Publication Title: | Current Medical Research and Opinion | ||||
| Publisher: | Informa Healthcare | ||||
| ISSN: | 0300-7995 | ||||
| Official Date: | June 2008 | ||||
| Dates: |
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| Volume: | Vol.24 | ||||
| Number: | No.6 | ||||
| Number of Pages: | 9 | ||||
| Page Range: | pp. 1635-1643 | ||||
| DOI: | 10.1185/03007990802131215 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
Data sourced from Thomson Reuters' Web of Knowledge
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