The Library
Minimally invasive spatial and temporal concentration profiling within working glucose biosensors
Tools
Tools
Tools
Burt, David P. and Unwin, Patrick R. (2008) Minimally invasive spatial and temporal concentration profiling within working glucose biosensors. Electrochemistry Communications, Vol.10 (No.6). pp. 934-937. doi:10.1016/j.elecom.2008.04.019 ISSN 1388-2481.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1016/j.elecom.2008.04.019
Abstract
The time-dependent evolution of analyte during the operation of working glucose biosensors has been profiled using a carbon fibre microelectrode (CFE). A simple procedure for the fabrication of minimally invasive CFE probes (<8 mu m maximum diameter) is described. By positioning the CFE at well-defined distances from a working biosensor surface it has been possible to track the concentration of ferrocyanide, generated in the enzymatic assay for glucose, as a function of space and time. The results indicate that on the timescale of operation of typical glucose biosensors, the enzyme-mediated oxidation of glucose only occurs to a significant extent in a thin layer close to the sensor surface. In much of the analyte volume the reaction is negligible, contrary to present consensus. (C) 2008 Elsevier B.V. All rights reserved.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | Q Science > QD Chemistry R Medicine > R Medicine (General) |
||||
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
| Library of Congress Subject Headings (LCSH): | Biosensors, Gluscose, Ultramicroelectrodes, Scanning electrochemical microscopy | ||||
| Journal or Publication Title: | Electrochemistry Communications | ||||
| Publisher: | Elsevier Inc. | ||||
| ISSN: | 1388-2481 | ||||
| Official Date: | June 2008 | ||||
| Dates: |
|
||||
| Volume: | Vol.10 | ||||
| Number: | No.6 | ||||
| Number of Pages: | 4 | ||||
| Page Range: | pp. 934-937 | ||||
| DOI: | 10.1016/j.elecom.2008.04.019 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
