The Library
Surface conductance in seamless microtubules
Tools
Dixon, J. M. (John M.), Chelminiak, P. and Tuszynski, J. A. (2008) Surface conductance in seamless microtubules. Physica A: Statistical Mechanics and its Applications, Volume 387 (Numbers 16-17). pp. 4183-4194. doi:10.1016/j.physa.2008.02.044 ISSN 0378-4371 .
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1016/j.physa.2008.02.044
Abstract
The cyto-architecture of eukaryotic cells contains self-assembled long cylinder-like structures called microtubules (MTs) which play an important role in a number of cellular activities such as cell division, motility, information processing and intracellular transport. In this paper we present a theoretical analysis of the surface conductance of a single seamless MT by representing each tubulin dimer as a resistor. Periodic boundary conditions were utilised both lengthwise (so the MT is pictured as a very large toroidal structure) and around its circumference. Firstly we have investigated the conductance matrix and found the eigenvalues and eigenvectors exactly. Then Wu's formula has been used to calculate the conductance in terms of them numerically. To check our results we have performed a series of computer simulations of random walks on the lattice of monomers utilising the widely known relationship between such a stochastic process and the theory of electrical networks. We obtain very good agreement between the two approaches. (c) 2008 Elsevier B.V. All rights reserved.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QC Physics T Technology > TK Electrical engineering. Electronics Nuclear engineering |
||||
Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering Faculty of Science, Engineering and Medicine > Science > Physics |
||||
Library of Congress Subject Headings (LCSH): | Microtubules, Eukaryotic cells, Electric resistors, Random walks (Mathematics) | ||||
Journal or Publication Title: | Physica A: Statistical Mechanics and its Applications | ||||
Publisher: | Elsevier BV | ||||
ISSN: | 0378-4371 | ||||
Official Date: | 1 July 2008 | ||||
Dates: |
|
||||
Volume: | Volume 387 | ||||
Number: | Numbers 16-17 | ||||
Number of Pages: | 12 | ||||
Page Range: | pp. 4183-4194 | ||||
DOI: | 10.1016/j.physa.2008.02.044 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Funder: | Leverhulme Trust (LT) |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |