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EuroQol EQ-5D and condition-specific measures of health outcome in women with urinary incontinence : reliability, validity and responsiveness
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Haywood, Kirstie L., Garratt, Andrew M., Lall, Ranjit, Smith, Jan Fereday and Lamb, S. E. (Sallie E.) (2008) EuroQol EQ-5D and condition-specific measures of health outcome in women with urinary incontinence : reliability, validity and responsiveness. Quality of Life Research, Volume 17 (Number 3). pp. 475-483. doi:10.1007/s11136-008-9311-z ISSN 0962-9343.
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Official URL: http://dx.doi.org/10.1007/s11136-008-9311-z
Abstract
Objectives To evaluate the measurement properties of the EuroQoL EQ-5D and two condition-specific patient-reported outcome measures-the Symptom Severity Index (SSI) and the Urinary Incontinence-Specific Quality of Life instrument (I-QoL)-in women with urinary incontinence.
Methods A questionnaire comprising all instruments was completed by women taking part in a clinical trial of physiotherapy for urinary incontinence. Follow-up questionnaires were at 6 weeks and 5 months. Data quality, internal consistency reliability, validity and responsiveness were assessed.
Results One hundred and seventy-four patients taking part in the clinical trial completed the questionnaire. Instruments had low levels of missing data. The EQ-5D had a large ceiling effect and poor responsiveness. The SSI had poor validity and responsiveness. The I-QoL had levels of reliability that supported application in group assessment, and in some cases, individual assessment, and good evidence of validity. The I-QoL was the most responsive instrument at both 6 weeks and 5 months.
Conclusion The I-QoL was the best performing instrument and is recommended as a continence-specific measure of quality of life in a clinical trial setting. The SSI and EQ-5D are not recommended. Alternative generic instruments, which support economic evaluation, require further evaluation in trials of female urinary incontinence.
| Item Type: | Journal Article | ||||
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| Subjects: | H Social Sciences > HV Social pathology. Social and public welfare R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine R Medicine > RT Nursing |
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| Divisions: | Faculty of Social Sciences > School of Health and Social Studies Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Urinary incontinence -- Treatment, Clinical trials, Women -- Diseases -- Treatment, Women's health services | ||||
| Journal or Publication Title: | Quality of Life Research | ||||
| Publisher: | Springer Netherlands | ||||
| ISSN: | 0962-9343 | ||||
| Official Date: | April 2008 | ||||
| Dates: |
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| Volume: | Volume 17 | ||||
| Number: | Number 3 | ||||
| Number of Pages: | 9 | ||||
| Page Range: | pp. 475-483 | ||||
| DOI: | 10.1007/s11136-008-9311-z | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Funder: | Physiotherapy Research Foundation (Australian Physiotherapy Association) |
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